PURPOSE Randomized comparisons of idarubicin (IDA) with daunorubicin (DNR) show that in adults with acute myeloid leukemia (AML), IDA achieves higher remission rates and longer remission durations. In Children's Cancer Group Pilot Study CCG-2941, we assessed toxicity and feasibility of substituting 4 mg of DNR with 1 mg of IDA in intensive-timing daunorubicin-based induction therapy (DNR/DNR) u...

The author comments on the potential of integrative data analysis (IDA) as a new methodological activity and on some of the topics that were discussed in the 5 articles in this special issue. One topic is the extent to which IDA will be used to provide conclusive summaries regarding the strength of evidence for well-specified questions versus to provide new information that goes beyond the simp...

AIM To investigate the cost effectiveness of routine small bowel biopsies (SBBs) in patients with iron deficiency anemia (IDA) independent of their celiac disease (CD) serology test results. METHODS We used a state transition Markov model. Two strategies were compared: routine SBBs during esophagogastroduodenoscopy (EGD) in all patients with IDA regardless their celiac serology status (strate...

OBJECTIVE Ten percent of adults presenting with iron deficiency anaemia (IDA) have underlying cancer. This analysis - the Iron Deficiency as an Indicator Of Malignancy (IDIOM) study - was undertaken to assess whether five simple clinical parameters can usefully predict the likelihood of gastrointestinal (GI) malignancy on subsequent investigation of patients with IDA. DESIGN Retrospective obs...

History records that Aceh has been hit by earthquakes several times, including the largest recorded, on December 26, 2004 with a magnitude of 9.3 SR. In connection history disasters have occurred, there is need for safety and disaster preparedness. It very important to conduct feasibility study existing public buildings used in preparedness vulnerability against earthquakes. The type building d...

Evidence of discrete scale invariance (DSI) in daytime healthy heart rate variability (HRV) is presented based on the log-periodic power law scaling of the heart beat interval increment. Our analysis suggests multiple DSI groups and a dynamic cascading process. A cascade model is presented to simulate such a property.

A simple hands-on model for illustrating the concept of isotope dilution analysis (IDA) has been devised. The consists two sets beads different sizes, with one set representing atoms analyte and other solvent water molecules. Phase separation is mimicked by sieving beads, results are detected according to color beads. In this paper, following three IDA methods illustrated using model: (1) direc...

Necessary and sufficient conditions are given to guarantee associativity of algebras and co-algebras. As main application, it is discussed the associativity of the tensor algebra T (V ) of a free module V over any commutative ring R. 1. Review of basic definitions Recall that a vector space A, or more generally a (free) module over a commutative ring R is an R-algebra if a multiplication map mA...