background: given the lack of consistency in the literature regarding the reliability of the ankle-brachial index (abi) as a valid screening tool and an independent risk indicator of cardiovascular events and mortality, we compared it with angiography as a reference standard test. methods: this case-control study, conducted between 2010 and 2011 in tehran heart center, recruited 362 angiographi...

Cardiovascular disease (CAD) screening in asymptomatic patients with diabetes mellitus is controversial. An exercise stress test is a safe and effective initial testing for Ischemic Heart Disease (IHD) screening. Treadmill stress test is not the best screening method for a particular patient who is not able to exercise, abnormal electrocardiogram (ECG) or positive exercise treadmill test (ETT) ...

OBJECTIVES Although ischemic electrocardiographic (ECG) changes during dipyridamole or adenosine infusion have been reported as a marker for severe coronary artery disease (CAD), few studies have focused on ST-segment changes with adenosine triphosphate (ATP)-loading myocardial single-photon emission computed tomography (SPECT). METHODS AND SUBJECTS Between January 2003 and August 2008, 4650 ...

Coronary artery chronic total occlusions (CTOs) are an exacerbation of stable coronary artery disease (CAD) with advanced calcification. CTOs are defined as 100% coronary occlusions with Thrombolysis in Myocardial Infarction grade 0 flow persisting for >3 months. National database registries and large single-center series suggest that in patients with CAD the overall incidence of CTOs may vary ...

Coronary artery chronic total occlusions (CTOs) are an exacerbation of stable coronary artery disease (CAD) with advanced calcification. CTOs are defined as 100% coronary occlusions with Thrombolysis in Myocardial Infarction grade 0 flow persisting for >3 months. National database registries and large single-center series suggest that in patients with CAD the overall incidence of CTOs may vary ...

Background: Coronary artery disease (CAD) is a multifactorial and heterogenic disease. Recently, genome-wide association studies have reported that rs1333040 (C/T) and rs1004638 (A/T) single nucleotide polymorphisms (SNPs) in the 9p21 locus have very strong association with CAD. This study aimed to examine these associations in Southwest of Iran. Methods: Blood samples were collected from 200 C...

BACKGROUND Previous studies have demonstrated the relevance of left coronary artery dominance in the outcome and prognosis of obstructive coronary artery disease (CAD). However, no studies have investigated the influence of coronary vessel dominance on non obstructive CAD. The aim of this study was to establish the association of left and mixed dominance of the major epicardial arteries with th...

Myocardial perfusion imaging with adenosine triphosphate (ATP) has been used increasingly to diagnose coronary artery disease (CAD) and assess risk for this disease. This study compared absolute myocardial blood flow (MBF) and myocardial flow reserve index (MFR) with ATP and dipyridamole (DIP) in patients with CAD. MBF was quantified by 15O-H2O PET in 21 patients with CAD (17 male, 4 female), a...

background: diagnosis of coronary artery disease (cad) in early stages is vital in decreasing mortality by reducing the risk factors. the aim of this study was to investigate the association between erectile dysfunction (ed) and cad. methods: a total of 200 patients were divided into four groups according to their angiography results: group 1 (g1, n = 59): patients with one-vessel disease (1-vd...