A naphthalimide-based fluorescent ensemble probe NPC for selectively detecting His in aqueous solution (10 mM HEPES, pH 7.4) has been reported. Moreover, the application of NPC in in vivo (both in Hela cells and in C. elegans) fluorescence imaging was carried out as well.

Background. Success of radiotherapy relies on accurate dose delivery. In vivo dosimetry improves control of treatment quality. Patients and methods. In vivo dosimetry with commercial diodes was performed in 209 rectal cancer patients treated with four-field box technique. The diodes measured either entrance or exit dose in each treatment field. The results were compared to the planned values an...

Multimodal nanoprobes have attracted intensive attentions since they can integrate various imaging modalities to obtain complementary merits of single modality. Meanwhile, recent interest in laser-induced photoacoustic imaging is rapidly growing due to its unique advantages in visualizing tissue structure and function with high spatial resolution and satisfactory imaging depth. In this review, ...

Near-infrared fluorescent proteins, iRFPs, are recently developed genetically encoded fluorescent probes for deep-tissue in vivo imaging. Their functions depend on the corresponding fluorescence efficiencies and electronic excited state properties. Here we report the electronic excited state deactivation dynamics of the most red-shifted iRFPs: iRFP702, iRFP713 and iRFP720. Complementary measure...

The lack of efficient detection techniques has so far prevented ultrasound-modulated optical tomography from achieving maturity. By applying a quantum spectral filter based on spectral-hole burning, one modulation sideband of the ultrasound-modulated diffuse photons can be efficiently selected while the DC and the other sidebands are blocked. This technique features a large etendue as well as t...