Positive selection or adaptive evolution is thought to be responsible, at least some of the time, for the rapid accumulation of advantageous changes in protein-coding genes. The origin of new enzymatic functions, erection of barriers to heterospecific fertilization, and evasion of host response by pathogens, among other things, are thought to be instances of adaptive evolution. Detecting positi...

We consider the orthogonal polynomials on [−1, 1] with respect to the weight wc (x) = h (x) (1− x) (1 + x) Ξc (x) , α, β > −1, where h is real analytic and strictly positive on [−1, 1], and Ξc is a step-like function: Ξc(x) = 1 for x ∈ [−1, 0) and Ξc(x) = c, c > 0, for x ∈ [0, 1]. We obtain strong uniform asymptotics of the monic orthogonal polynomials in C, as well as first terms of the asympt...

Food assistance to the needy in this country was initiated in legislation with the interesting title "The Potato Control Act of 1935." Nobody thought its primary aim was to help the poor. Rather, it was to dispose of surplus commodities in order to support farm prices-that is, to help the farmers. This initial objective is why the program was made the responsibility of the Department of Agricul...

We describe a case of a 42-year-old man, with a previous episode of angina and a normal ECG and serum cardiac markers, and a two months later finding of biphasic T wave in leads V2-V3 and deeply inverted T wave in V4-V5 at a asymptomatic occupational evaluation. This is a typical ECG pattern of Wellens' syndrome. A subsequent coronary angiography showed a critical stenosis of proximal left ante...

We consider the problem of computing the shortest schedule of the intervals [j2-‘, (j + 1)2-‘), for 0 < j < 2’ 1 and 1 < i < k such that separation of intersecting intervals is at least R. This problem arises in an application of wavelets to medical imaging. It is a generalization of the graph separation problem for the intersection graph of the intervals, which is to assign the numbers 1 to Zk...

Closely related genres have complex interrelations. An antecedent genre can constrain a subsequent genre, but changing rhetorical situations can lead to distinctions between an antecedent and its descendent. In this study, we assess two genres of detective fiction to determine their hierarchical relation to one another. We use the Gramulator, a computational tool that identifies indicative lexi...