The effect of the concomitant administration of the antifungal drugs ketoconazole (KTC) and itraconazole (ITC) on the pharmacokinetics of ciprofloxacin (CIP) following short- and long-term administration in mice was investigated. Animals received either a dose of CIP (20 mg/kg, i.p.), CIP (20 mg/kg, i.p.) together with KTC (50 mg/kg, p.o.) or CIP (20 mg/kg, i.p.) and ITC (30 mg/kg, p.o.). The s...

Brassicales contain a myrosinase enzyme that hydrolyzes glucosinolates to form toxic isothiocyanates (ITC), as a defense against bacteria, fungi, insects and herbivores including man. Low levels of ITC trigger a host defense system in mammals that protects them against chronic diseases. Because humans typically cook their brassica vegetables, destroying myrosinase, there is a great interest in ...

BACKGROUND The most appropriate surgical procedure for multinodular goiter (MNG) remains under debate. Incidental thyroid carcinoma (ITC) is often identified on histopathological examination after thyroidectomy performed for presumed benign MNG. AIM OF THE STUDY The aim of the study was to determine the value of radical surgery for MNG patients considering the prevalence of ITC diagnosed post...

Cooperative binding pervades Nature. This review discusses the use of isothermal titration calorimetry (ITC) in the identification and characterisation of cooperativity in biological interactions. ITC has broad scope in the analysis of cooperativity as it determines binding stiochiometries, affinities and thermodynamic parameters, including enthalpy and entropy in a single experiment. Examples ...

Current Isothermal Titration Calorimetry (ITC) data in the literature have relatively high errors in the measured enthalpies of protein-ligand binding reactions. There is a need for universal validation standards for titration calorimeters. Several inorganic salt co-precipitation and buffer protonation reactions have been suggested as possible enthalpy standards. The performances of several com...

Hydroxy isothiocyanates (ITCs), including some new derivatives of naturally occurring compounds, were synthesized and their minimum inhibitory, minimum fungicidal, and minimum bactericidal concentrations for Aspergillus niger, Aspergillus fumigatus, Staphylococcus aureus, and Escherichia coli were estimated. These compounds were strongly antimicrobial; for example, 2-(4-hydroxyphenyl) ethyl ITC...

Prospects for genetic improvement of Eucalyptus cladocalyx in Western Australia Andrew Callister, David Bush, Sally Collins, Wayne Davis 1 ITC Forestry, PO Box 1421 Albany, WA 6331. [email protected] 2 Ensis Genetics, PO Box E4008 Kingston ACT 2604. [email protected] ITC Forestry, PO Box 1421 Albany, WA 6331. [email protected] 4 ITC Forestry, PO Box 1421 Alba...

This material is presented to ensure timely dissemination of technical work and the document will be distributed free of charge among ITC-irst research partners. The Editorial Office of the Istituto Trentino di Cultura (ITC) publishes every year a list of all technical publications co-authored by ITC-irst researchers, including abstracts and full bibliographical notes. Exchange of publications ...

An interactive programme, incorporating a deterministic model of tsetse (Diptera: Glossinidae) populations, was developed to predict the cost and effect of different control techniques applied singly or together. Its value was exemplified by using it to compare: (i) the sterile insect technique (SIT), involving weekly releases optimized at three sterile males for each wild male, and (ii) insect...

the aim of this study is to present a theoretical framework in order to understand the relationship between emotional intelligence constructs and organizational culture. in this research, in addition to the study of emotional intelligence and organizational culture, entrepreneurial culture theoretical basis and its relationship with the emotional intelligence are analyzed. therefore, the confir...