نتایج جستجو برای: immunotoxic effect

تعداد نتایج: 1641878  

Journal: :The American journal of clinical nutrition 2008
Belén Morón Angel Cebolla Hamid Manyani Moisés Alvarez-Maqueda Manuel Megías María Del Carmen Thomas Manuel Carlos López Carolina Sousa

BACKGROUND Celiac disease is an immune-mediated enteropathy caused by the ingestion of gluten, a protein fraction found in certain cereals. Immunotoxic gluten peptides that are recalcitrant to degradation of digestive enzymes appear to trigger celiac syndromes. A 33-mer peptide from alpha-2 gliadin has been identified as a principal contributor to gluten immunotoxicity. A gluten-free diet is th...

Journal: :Toxicological sciences : an official journal of the Society of Toxicology 2001
T L Bunn P J Parsons E Kao R R Dietert

Previous rat studies with lead (Pb) have shown that exposure throughout the full gestational period results in persistent immunotoxicity detectable in both juvenile and adult offspring. Gender differences are also evident. However, little is known about the persistent immunotoxic effects of Pb when administered during specific stages of embryonic development. Adult Sprague-Dawley female rats we...

Journal: :International Journal of Applied Pharmaceutics 2023

Objective: In the current study, an in silico approach has been utilized to investigate anti-SARS CoV 2 activity of some derivatives Tetrahydro curcumin (THC), a metabolite. Methods: BioVia Draw 2017 was used design 168 THC derivatives. All were docked using Maestro Schrodinger programme. Depending on docking score, ADME, drug-likeness, and toxicity prediction few conducted. Results: designed. ...

2016
Christina Giannakou Margriet VDZ Park Wim H de Jong Henk van Loveren Rob J Vandebriel Robert E Geertsma

Nanomaterials (NMs) are attractive for biomedical and pharmaceutical applications because of their unique physicochemical and biological properties. A major application area of NMs is drug delivery. Many nanomedicinal products (NMPs) currently on the market or in clinical trials are most often based on liposomal products or polymer conjugates. NMPs can be designed to target specific tissues, eg...

Journal: :International Journal of Pharmacy and Pharmaceutical Sciences 2017

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