نتایج جستجو برای: immunoblot

تعداد نتایج: 6290  

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2009
Ai-Ming Yu Jun Qu Melanie A Felmlee Jin Cao Xi-Ling Jiang

Accurate quantification of cytochrome P450 (P450) protein contents is essential for reliable assessment of drug safety, including the prediction of in vivo clearance from in vitro metabolism data, which may be hampered by the use of uncharacterized standards and existence of unknown allelic isozymes. Therefore, this study aimed to delineate the variability in absolute quantification of polymorp...

Journal: :The Journal of clinical investigation 1994
G S Wand C Waltman C S Martin M E McCaul M A Levine D Wolfgang

We evaluated G-proteins that are components of adenylyl cyclase (AC) signal transduction in erythrocyte and lymphocyte membranes from 26 family history positive (FHP) non-alcoholic and 26 family history negative (FHN) nonalcoholic subjects. Subjects were classified as FHP if their father met criteria for alcohol dependence; as FHN, if there was no history of alcoholism in any first or second de...

2014
Laurian Zuidmeer-Jongejan Montserrat Fernández-Rivas Marcel GT Winter Jaap H Akkerdaas Colin Summers Ans Lebens André C Knulst Piet Schilte Peter Briza Gabriele Gadermaier Ronald van Ree

BACKGROUND Oil body-associated allergens such as oleosins have been reported for important allergenic foods such as peanut, sesame and hazelnut. Here we investigate whether oil body associated proteins (OAPs) are linked with specific clinical phenotypes and whether they are represented in skin prick test (SPT) reagents. METHODS A hazelnut OAP fraction was characterized by mass-spectrometry (M...

Journal: :Journal of clinical microbiology 1994
H Kato N Kato K Watanabe K Ueno H Ushijima S Hashira T Abe

Pulsed-field gel electrophoresis (PFGE) analysis of restriction pattern polymorphism was applied to type Clostridium difficile isolated from neonates hospitalized in a neonatal intensive care unit, and the results were compared with those of immunoblot analysis. C. difficile was isolated from fecal specimens of 41 (61%) of 67 neonates during a 5-month investigation. All of these neonates were a...

Journal: :International immunology 2005
András Lakos Emoke Ferenczi Sámuel Komoly Marta Granström

The diagnosis of neuroborreliosis (NB)--a serious complication of Lyme disease--relies on demonstration of intrathecal borrelia antibody production. We hypothesized that if a qualitative difference between the cerebrospinal fluid and the serum immunoblot-banding patterns was observed, then the borrelia antibodies found in the CSF could not be the result of leakage of serum antibodies to the CSF...

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