نتایج جستجو برای: imidazolidine 2
تعداد نتایج: 2525346 فیلتر نتایج به سال:
In the title compound, C15H18N2O2S, the 2,3-di-hydro-1-benzo-thio-pyran ring adopts a sofa conformation and the hydantoin ring is twisted with respect to the benzene ring at 78.73 (17)°. In the crystal, pairs of N-H⋯O hydrogen bonds link the mol-ecules into inversion dimers.
The emergence of strains of Schistosoma resistant to praziquantel has drawn attention to the search for new schistosomacide drugs. Imidazolidinic derivatives have performed outstandingly against adult S. mansoni worms when evaluated in vitro. The molecular modification of imidazolidine by way of bioisosteric replacement gives rise to variations in its biological response. This study verifies th...
The title compound, C(15)H(22)N(2)O(3), has been isolated as a by-product of an oxidative cleavage of the C-C bond linking two five-membered rings of 1,3-dicyclo-hexyl-5-(3-oxo-2,3-dihydro-benzofuran-2-yl)imidazolidine-2,4-dione. Individual mol-ecular units are engaged in weak C=O⋯C=O inter-actions [O⋯C = 2.814 (10) and 2.871 (11) Å], leading to the formation of supra-molecular chains which clo...
The title compound, C(20)H(19)Cl(2)N(5)O(2)S, was obtained from the reaction of 4-chloro-benzoyl isothio-cyanate with diethyl-ene-triamine. The imidazolidine ring is slightly twisted with an N-C-C-N torsion angle of 15.4 (4)°, while the thio-urea moiety maintains its trans-cis geometry. The mol-ecule is stabilized by intramolecular N-H⋯O hydrogen bonds. The crystal structure features N-H⋯O, N-H...
In the title compound, C(11)H(19)N(3)O(5), the six-membered ring displays a half-chair conformation and the imidazolidine ring is essentially planar (r.m.s. deviation = 0.088 Å). An inter-molecular hydrogen bond between the hy-droxy O atom and a nitro O atom stabilizes the crystal packing.
The crystal structure determination of the title compound, C(15)H(14)N(2)O, confirms the cis relationship between the phenyl groups at the 4- and 5-positions on the imidazolidine ring. The dihedral angle between the two phenyl rings is 48.14 (6)°. In the crystal structure, inter-molecular N-H⋯O hydrogen bonds link mol-ecules into centrosymmetric dimers. These dimers are, in turn, linked into a ...
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