introduction: escherichia coli is one of the important pathogens in human with global importance. because of the necessity for identification and the use of novel antibacterial compounds against e. coli , in this present study we focused on the antibacterial effects of synthesized thiazole, imidazole and tetrahydropyridine derivatives on e. coli .   methods : for evaluation of antibacterial eff...

in the present study, an attempt has been made to synthesize 3-methyl-4-arylmethylene isoxazole-5(4h)-one derivatives through sonication of hydroxylamine hydrochloride, ethyl acetoacetate and benzaldehyde derivatives in the presence of imidazole as a novel and effective catalyst in aqueous media. this green reaction under ultrasound irradiation has advantageous compared to conventional procedur...

The FixL heme-based sensor, despite its low affinity for oxygen, is much more reactive than myoglobin toward the large polar ligand imidazole. To determine which features of a myoglobin heme pocket favor binding of imidazole, we have measured binding of this ligand to the FixL heme domain, elephant myoglobin, wild-type sperm whale myoglobin, and sperm whale myoglobins having alanine, valine, th...

The cover picture shows a DNA recognition system that imitates the dimer formation of natural transcription factor pairs. Pyrrole-imidazole polyamides bind to programmable sequences and enable us target specific genomic regions. We have developed artificial factors by expanding function pyrrole-imidazole with other compounds (e.g., peptides epigenetic modulators), achieving gene regulation chem...

Alkyl chain length influences ionicity, conductivity, and viscosity of lithium imidazole salts.

A new series of D-π-A type imidazole derivatives have been synthesized and characterized. Two corresponding imidazolium salts (iodine and hexafluorophosphate) were prepared from the imidazole compound. Their electron-withdrawing ability can be largely tunable by salt formation reaction or ion exchange. UV-vis absorption and single-photon fluorescence spectra have been systematically investigate...

Azido Coordination, Imidazole Adducts, Structural Interconversion A number of mixed-ligand complexes of cobalt(III) containing coordinated azide ion, acetylacetonate anion and the neutral base imidazole and, having the general formula [Co(acac)2(N3)(Im)] (Im = imidazole or its derivatives) have been synthesised by the reaction of K[rrans-Co(acac)2(N3)2] with the biologically active ligand imida...

derivatives of thiazolidinone ring systems are known to act as anti-hiv infections , analgesic, anti-bacterial, anti-convulsant, anti parasitic, potential anti-inflammatory and herbicidal agents. due biological activities of thiazolidinones ring, several methods for their synthesis have been illustrated in literature. imidazolidine-2-thiones were synthesized by the oxidative cyclization of 1-be...

in the present study, some new bis-imidazole derivatives have been prepared through four-components condensation of 2,6-bis (4-aminophenyl)-4-p-tolylpyridine, benzaldehyde derivatives, benzil and ammonium acetate in presence of acetic acid. the present methodology offers several advantages such as good yields, simple procedure, milder conditions and the possibility of introducing a variety of s...