The aim of the present study was to evaluate the antitumor potential of iminoflavones in in vitro and in vivo anticancer models. Preliminary screening in various cancer cell lines revealed four potential iminoflavones out of which IMF-8 was taken based on its activity against colon cancer cells. This was further confirmed by observing the nuclear changes in the cells by AO/EB and Hoechst 33342 ...

In this article, we interrogate the policy response of the International Monetary Fund (IMF) to the global financial crisis, and discuss the likely global health implications, especially in low-income countries. In doing so, we ask if the IMF has meaningfully loosened its fiscal deficit targets in light of the economic challenges posed by the financial crisis and adjusted its macro-economic pol...

Observational constraints on the theory of the IMF are reviewed. These observations include the new result that star formation is very rapid, usually going from start to finish in only 1 or 2 dynamical times on a wide range of scales. This result, combined with the observation that the IMF is independent of cluster density over a factor of several hundred, implies that protostar coagulation dur...

In this work we explore the effects of adopting an initial mass function (IMF) variable in time on the chemical evolution of the Galaxy. In order to do that we adopt a chemical evolution model which assumes two main infall episodes for the formation of the Galaxy. We study the effects on such a model of different IMFs. First, we use a theoretical one based on the statistical description of the ...

The JAK2 V617F mutation has recently been described as an essential oncogenic event associated with polycythemia vera (PV), idiopathic myelofibrosis (IMF), and essential thrombocythemia. This mutation has been detected in all myeloid lineages but has not yet been detected in lymphoid cells. This raises the question whether this molecular event occurs in a true lymphomyeloid progenitor cell. In ...

Suitable intramuscular fat (IMF) content improves porcine meat quality. The vital genes regulating IMF deposition are necessary for the selection and breeding of an IMF trait. However, the effect and mechanism of PDGFRα on IMF deposition are still unclear. Here, PDGFRα is moderately expressed in porcine longissimus dorsi muscle (LD), whereas it highly expressed in white adipose tissue (WAT). Mo...

Whether the stellar initial mass function (IMF) is universal or is instead sensitive to environmental conditions is of critical importance: The IMF influences most observable properties of stellar populations and thus galaxies, and detecting variations in the IMF could provide deep insights into the star formation process. This review critically examines reports of IMF variations, with a view t...

We report on field-aligned currents (FAC) obtained from precise magnetic field measurements made onboard the Orsted and Magsat satellites when the interplanetary magnetic field (IMF) was near zero. We found that Region 1/Region 2 currents persist through southward IMF, IMF -• 0, and northward IMF; also the central area of both the northern and southern polar caps is always filled with FACs, eve...

INTRODUCTION: The use of intermaxillary fixation (IMF) in the treatment of maxillofacial trauma represents the cornerstone of fracture reduction and immobilization. Many modalities of IMF have been described. Recently, to overcome the cumbersome procedure of tooth borne appliances, miniimplants have been introduced into clinical practice. OBJECTIVES: To evaluate the effectiveness of using mini-...

The F-ATPases synthesize ATP using a transmembrane ionmotive force (IMF) established by the electron transport chain. This transduction involves first converting the IMF to a rotary torque in the transmembrane Fo portion. This torque is communicated from Fo to the F1 portion where the energy is used to release the newly synthesized ATP from the catalytic sites according to Boyer's binding chang...