Topological knots are found in a considerable number of protein structures, but it is not clear how they knot and fold within the cellular environment. We investigated the behavior of knotted protein molecules as they are first synthesized by the ribosome using a cell-free translation system. We found that newly translated knotted proteins can spontaneously self-tie and do not require the assis...

Arch Dis Child January 2011 Vol 96 No 1 An 8-year-old boy with cystic fi brosis was planned for a course of home intravenous antibiotics. A peripherally inserted central catheter (PICC) was inserted from his left wrist on the third attempt. By the third day, he had developed a swollen red forearm. Clinically, a small non-tender nodule was palpable 1 cm proximal to a healthy insertion site. The ...

The aim of this study was to report a clinical case ileocaecal node in the visceral surgery department Donka. ileosigmoid or knot (ISK), is an exceptional entity, it surgical emergency characterized by strangulation small intestine forming around base sigmoid colon with risk rapid necrosis intestine. And colon. preoperative diagnosis condition difficult because its rarity and atypical radiograp...

In this paper we suggest an entirely new strategy for the dexterous manipulation of a linear flexible object, such as rope or a cable, with a high-speed manipulator. We deal with a flexible rope as one example of the linear flexible object. The strategy involves manipulating the object at highspeed. By moving the robot at high-speed, we can assume that the dynamic behaviour of the flexible rope...