The novel compound 2-{[4-(4-bromophenyl)piperazin-1-yl)]methyl}-4-(3-chlorophenyl-5-(4-methoxyphenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione is obtained in good yield via a three-step protocol. product’s structure assigned by HRMS, IR, 1H and 13C NMR experiments.

Abstract Novel hydrazone and 1,2,4-triazole-3-thione derivatives were obtained via the reaction of N 1 , 3 ,2-triaryl-6-hydroxy-6-methyl-4-oxocyclohexane-1,3-dicarboxamides with acid hydrazides thiosemicarbazide, respectively. Structure products was proved using IR H NMR spectroscopy methods. Some synthesized compounds tested for antimicrobial activity

The reaction of the ligand Et4todit (4,5,6,7-Tetrathiocino-[1,2-b:3,4-b']diimidazolyl-1,3,8,10-tetraethyl-2,9-dithione) with gold complexes leads to the dinuclear gold(I) complexes [{Au(C6F5)}2(Et4todit)] and [Au(Et4todit)]2(OTf)2, which do not contain any gold-gold interactions, or to the gold(III) derivative [{Au(C6F5)3}2(Et4todit)]. The crystal structures have been established by X-ray diffr...

Tuberculosis (TB) ranks second, next to AIDS making it most formidable disease if the present age. One of the crucial enzymes involved in cell wall synthesis of Mycobacterium tuberculosis, InhA (enoyl acyl carrier protein reductase) has been authenticated as an effective target for anti-mycobacterial drug development. In the current work, we have developed novel derivatives of 1,2,4-triazole-5-...

A solvent-extraction spectrophotometric technique is proposed as a new method for determination of trace quantities of vanadium. Sodium salt of 2-mercapto-pyridine-N-oxide (thione) forms a complex with vanadium instantaneously. The purple 1:2 complex is formed of pH 2.3, easily extracted in chloroform and shows strong absorbance at 500 nm. The extracted complex is found to obey Beer's law i...

In the mol-ecule of the title compound, C(14)H(18)N(2)O(2)S(2), the 1,3,5-thia-diazinane-2-thione ring adopts an envelope conformation with one of the N atoms at the flap position. The plane throught the five co-planar atoms of the heterocycle is oriented at a dihedral angle of 80.59 (8)° with respect to the aromatic ring. In the crystal structure, weak inter-molecular O-H⋯S inter-actions link ...

We present a series of compounds by exploiting the unusual 1,4-aryl shift observed for electron-rich 1,3-dithiole-2-thione and tetrathiafulvalene (TTF) derivatives in the presence of perchloric acid. The mechanistic features of this rearrangement are discussed since this synthetic strategy provides an alternative route for the synthesis and functionalisation of sulfur rich compounds including r...

Two selenated analogues of the all-sulfur single-component molecular conductor [Ni(Et-thiazdt)2] (Et-thiazdt = N-ethylthiazoline-2-thione-4,5-dithiolate) have been prepared from their precursor radical-anion complexes. Replacement thione by a selenone moiety gives neutral [Ni(Et-thiazSedt)2] complex. It adopts an unprecedented solid-state organization (for nickel complexes), with formation perf...

The incorporation of heteroatoms into the backbone commodity polymers prepared by radical polymerization is an elegant way to confer (bio)degradability such materials. This could be achieved via ring-opening cyclic monomers. Thionolactones have recently been identified as promising comonomers for (rROP), but they react only with activated monomers acrylate and acrylamide derivatives. Herein, we...