Statistical machine learning focuses on non-parametric models that learn the minimum necessary to perform the targeted discrimination. For instance, in a binary classification problem, SVMs will only use the examples located within a boundary margin between the two classes to compute the optimal separation. However, one can consider other discrimination settings that use the entirety of the dat...

Observations among milk-drinking African nomads showed an unusual freedom from infection with Entamoeba histolytica compared with similar nomads taking a mixed diet. A controlled study among Maasai pastoralists showed that the administration of iron to correct their dietary iron deficiency sharply increased their susceptibility to amoebiasis. Examination of the milk of their Zebu cattle showed ...

BACKGROUND To achieve synthetic control over how a cell responds to other cells or the extracellular environment, it is important to reliably engineer proteins that can traffic and span the plasma membrane. Using a modular approach to assemble proteins, we identified the minimum necessary components required to engineer such membrane-spanning proteins with predictable orientation in mammalian c...

Ms. Guthrie's paper involves the final Privacy Regulations promulgated by the Department of Health and Human Services pursuant to HIPAA. Her thesis highlights three burdensome requirements which remain significant obstacles to the compliance date of April 14, 2003: (1) the need to undertake thorough preemption analyses, (2) lack of clarity surrounding the "Minimum Necessary Standard," and (3) c...

X ray procedures which involve fluoroscopy often give significant radiation doses to patients. A valuable radiation protection procedure is the adoption of a quality assurance programme which will ensure the continual production of optimal quality images with the minimum necessary dose to the patient. Various publications exist which provide information on quality assurance (QA) and constancy c...

BACKGROUND The Ministry of Health (MOH) in Zambia is currently operating with fewer than half of the health workers required to deliver basic health services. The MOH has developed a human resources for health (HRH) strategic plan to address the crisis through improved training, hiring, and retention. However, the projected success of each strategy or combination of strategies is unclear. MET...