نتایج جستجو برای: ie 86 antibody
تعداد نتایج: 242515 فیلتر نتایج به سال:
The 86-kilodalton immediate-early (IE) 2 protein (IE2-p86) of human cytomegalovirus (HCMV) is a multifunctional regulator of HCMV gene expression which appears to be essential for triggering the lytic replicative cycle. IE2-p86 functions as a promiscuous transactivator of both viral and cellular gene expression and can repress transcription from its own promoter. In this study we demonstrate th...
Glomerulonephritis (GN) due to infective endocarditis (IE) is well documented, but most available data are based on old autopsy series. To update information, we now present the largest biopsy-based clinicopathologic series on IE-associated GN. The study group included 49 patients (male-to-female ratio of 3.5:1) with a mean age of 48 years. The most common presenting feature was acute kidney in...
Because an enriched environment (EE) enhances T-cell activity and T-lymphocytes contribute to immunopathogenesis during heterologous dengue virus (DENV) infections, we hypothesised that an EE increases dengue severity. To compare single serotype (SS) and antibody-enhanced disease (AED) infections regimens, serial intraperitoneal were performed with DENV3 (genotype III) infected brain homogenate...
1.2 Machine failure A system is composed of 5 components, each of which is either working or broken. Consider an experiment that consists of observing the status of each component, and let the outcome of the experiment be given by the vector (x1, x2, x3, x4, x5), where xi = 1 if component i works and 0 if component i is broken. 1. How many outcomes are in the sample space of this experiment? 2....
Neoplastic transformation is a complex process that results from multiple changes in gene activities. Probably most of these are mutational, i.e. alterations in the genomic structure of DNA, but others may be due to adaptive changes wherein genes are expressed that are inappropriate to a stage of development or differentiation. In this commentary neoplastic development is discussed in the conte...
It is therefore very important to optimise the care of diabetic patients at primary, secondary and tertiary care level. Numerous clinical practice guidelines for management of diabetes have been compiled and circulated to health care workers, but despite this the level of diabetes care is still not ideal because of suboptimal implementation strategies. Guideline implementation problems are a si...
The contribution that antibody and delayed type hypersensitivity (DTH) make in promoting HSV-1 clearance from the infected cornea was investigated. Balb/c mice were immunized intravenously or subcutaneously with an attenuated strain of HSV-1 to generate hosts which were antibody-producing DTH-tolerant or antibody-producing DTH-responsive. Anti-mu serum treated mice were likewise sensitized intr...
Despite tremendous progress in understanding the nature of the immune system, the full diversity of an organism's antibody repertoire is unknown. We used high-throughput sequencing of the variable domain of the antibody heavy chain from 14 zebrafish to analyze VDJ usage and antibody sequence. Zebrafish were found to use between 50 and 86% of all possible VDJ combinations and shared a similar fr...
The prevalence, immunoglobulin class, and IgG subclass of antireticulin antibody in the serum samples of 32 patients with systemic sclerosis were investigated by indirect immunofluorescence on unfixed rodent tissue. Antireticulin antibody was present in 22/32 (69%) of patients and belonged to the IgG class in 19/22 (86%), the IgA class in 13/22 (59%), and the IgM class in 6/22 (27%) of positive...
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