نتایج جستجو برای: icu sedation
تعداد نتایج: 36058 فیلتر نتایج به سال:
Providing sedation and comfort for intensive care patients has evolved in the last few years. New approaches to improving outcomes for intensive care unit (ICU) patients include providing analgesia before adding sedation and recognizing dangerous adverse effects associated with sedative medications, such as prolonged effects of midazolam, propylene glycol toxicity with lorazepam, propofol infus...
Propofol is an intravenous sedative-hypnotic agent indicated for induction and maintenance of general anesthesia as well as for sedation of intubated, mechanically ventilated adults in intensive care units (ICU). Propofol is characterized by a phenolic structure similar to that of α-tocopherol, and presents antioxidant properties that have been demonstrated both in vitro and in vivo. The aim of...
UNLABELLED In the intensive care units (ICUs) sedation strategies have changed in the past decade towards less sedation and daily wake-up calls. Recent studies indicate that no sedation (after intubation) is most beneficial for patients. A smaller number of these patients have been assessed for post-traumatic stress disorder (PTSD) after ICU discharge, but none of them were assessed for deliriu...
This study aimed to investigate the clinical effectiveness of dexmedetomidine and midazolam for sedation of intensive care unit (ICU) patients requiring flexible fiberoptic bronchoscopy (FFB).This retrospective cohort study included 148 patients from the third ICU ward of the Second Affiliated Hospital of Harbin Medical University (Harbin, China) who received simultaneous invasive mechanical ve...
BACKGROUND This meta-analysis was performed to assess the influence of dexmedetomidine and propofol for adult intensive care unit (ICU) sedation, with respect to patient outcomes and adverse events. MATERIALS AND METHODS A systematic review was conducted of all randomized controlled trials exploring the clinical benefits of dexmedetomidine versus propofol for sedation in adult intensive care ...
CONTEXT Protocolized sedation and daily sedation interruption are 2 strategies to minimize sedation and reduce the duration of mechanical ventilation and intensive care unit (ICU) stay. We hypothesized that combining these strategies would augment the benefits. OBJECTIVE To compare protocolized sedation with protocolized sedation plus daily sedation interruption in critically ill patients. ...
BACKGROUND Sedatives and analgesics are administered to provide sedation and manage agitation and pain in most critically ill mechanically ventilated patients. Various sedation administration strategies including protocolized sedation and daily sedation interruption are used to mitigate drug pharmacokinetic limitations and minimize oversedation, thereby shortening the duration of mechanical ven...
Although the administration of sedatives is a commonplace activity in the ICU, few guidelines are available to aid the clinician in this practice. The first principle of sedative administration is to define the specific problem requiring sedation and to rationally choose the drug and depth of sedation appropriate for the indication. Next, the clinician must recognize the diverse and often unpre...
We tested if microcomputer-based measurements of heart rate variability and respiratory sinus arrhythmia (RSA) could be used as the basis of an objective sedation score. Measurements were obtained in eight ICU patients before, during and after physiotherapy. Patients were sedated with propofol and alfentanil and paralysed with atracurium. Mean ECG R-R interval showed little variation, changing ...
Optimal management of sedation, pain, agitation, and delirium in intensive care unit (ICU) involves systematic and multimodal approaches to provide comfort and safety. As one of the most widely used alpha 2-adrenergic receptor agonists, dexmedetomidine has become more and more popular for sedation and agitation in critically ill adult patients. The sedative, analgesic and opioid-sparing effects...
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