BACKGROUND Somatisation is highly prevalent in primary care (present in 25% of visiting patients) but often goes unrecognised. Non-recognition may lead to ineffective treatment, risk of iatrogenic harm, and excessive use of healthcare services. AIM To examine the effect of training on diagnosis of somatisation in routine clinical practice by general practitioners (GPs). DESIGN OF STUDY Clus...

To describe a patient with drug-induced parkinsonism whose baseline dopamine transporter SPECT resulted abnormal, but whose dopaminergic neuronal density was normal. Background: In vivo imaging techniques investigating presynaptic nigrostriatal function using dopamine transporter (DAT) SPECT or 18F-Dopa PET are currently considered to reliably distinguish a degenerative parkinsonism from a iatr...

P atients with connective tissue disease (CTD) may encompass a variety of respiratory manifestations, including: pleural disease; pulmonary hypertension; bronchial or bronchiolar disease; interstitial pneumonia; restrictive lung disease secondary to musculo-skeletal changes; and iatrogenic drug-induced lung disease. Patients also have an increased risk of opportunistic infections, often favoure...

LASIK is a surgical tehnique for the correction of refractive errors (myopia, hyperopia, astygmatism). It results in a reshape of the cornea with ocular surface and especially tear film disease. It is a cause for a iatrogenic dry eye syndrome. Neurogenic and inflamatory theory explain this disease. The main therapy of dry eye is the replacement with artificial tears.

Nephrogenic systemic fibrosis (NSF) is an iatrogenic fibrosing disorder that primarily affects individuals with chronic kidney disease (CKD) following exposure to gadolinium-based contrast agents (GBCAs) during imaging procedures. NSF is characterised by skin thickening, tethering and hyperpigmentation; flexion contractures of joints; and extracutaneous fibrosis. This article reviews the histor...

Three cases of probable iatrogenic transmission of Creutzfeldt-Jakob disease by neurosurgery are detailed together with a cluster of three cases in Eastern England possibly connected by dental procedures, and the development of Creutzfeldt-Jakob disease in a patient who had been in social contact with a familial case.

Oesophageal dysfunction can occur in a variety of musculoskeletal conditions, most notably the autoimmune connective tissue diseases. However, correlation between oesophageal symptoms and investigations is frequently poor. It is often uncertain whether symptoms are caused by the underlying disease or by its treatment. As the primary disease process may not be responsive to treatment, correctabl...

strongyloidiasis is a disease characterized by a diverse spectrum of unspecific manifestations that complicate its diagnosis. although, the course of its chronic form is usually benign, in cases of immunosuppression, iatrogenic or not, it can evolve to a hyperifection syndrome with even fatal complications. herein, we report a case of strongyloides stercoralis hyperinfection in a greek patient ...