Allocation of research funding, as well as promotion and tenure decisions, are increasingly made using indicators and impact factors drawn from citations to published work. A debate among scientometricians about proper normalization of citation counts has resolved with the creation of an Integrated Impact Indicator (I3) that solves a number of problems found among previously used indicators. Th...

Muscarinic M2, M4, and M2-M4 chimera receptors were transiently expressed in HEK-293 tsA201 cells, and agonist-dependent internalization of these receptors and recycling of internalized receptors were examined by measuring the amount of cell-surface receptors as [3H]N-methylscopolamine (NMS) binding activity. Coexpression of a dominant negative form of dynamin (DN-dynamin,dynamin K44A) greatly ...

Understanding the precise structure and function of the intracellular domains of G protein-coupled receptors is essential for understanding how receptors are regulated, and how they transduce their signals from the extracellular milieu to intracellular sites. To understand better the structure and function of the intracellular domain of the 5-hydroxytryptamine2A (5-HT2A) receptor, a model G(alp...

This study aims at investigating the acoustic correlates of supralaryngeal and muscular tension voice quality settings (VQS). Speech samples from 40 speakers were perceptually analyzed by means of the Vocal Profile Analysis Scheme (VPAS). Acoustic analysis comprised formant frequency (F1, F2 and F3) and intensity measurements (I1, I2 and I3) of seven Brazilian Portuguese vowels. Multivariate st...

Native nickel of composition Ni 96"3 ~, Fe 1"77 ~, and Co 0'69 ~ was found as tiny flakes up to o'75 mm across in a heavy mineral concentrate from stream sediments in the Jerry River, South Westland, New Zealand. The locality is approximately I3 km downstream from the original locality for awaruite (Ni~Fe), and it is shown that the nickel content of detrital grains increases with distance from ...

Pot culture experiment was conducted to evaluate the effect of different minisett corm sizes and integrated nutrient management practices on biological properties potting medium in elephant foot yam at Instructional Farm, College Agriculture, Vellayani, Thiruvananthapuram, Kerala during April 2018-November 2018. The treatments consisted three (s1-200 g, s2-300 g s3-400 g) five (i1-100 % NPK, i2...