Pigment disorders1,3 Hypopigmentation or depigmentation. Lesions demonstrate increased sharpness of borders under Wood lamp examination and fluoresce bright blue-white owing to the increased amount of dermal collagen illuminated. This results from decreased or absent intervening melanin. Vitiligo: patches, varying in location and extent. Tuberous sclerosis: patches; characteristic shapes are la...

Cutaneous T-cell lymphoma (CTCL) presenting with hypopigmented lesions is an uncommon clinical variant of the disease, usually described in dark-skinned patients. We report a case of hypopigmented CTCL in a 10-year-old boy. The disease has responded favorably to narrowband UVB therapy. This case illustrates the importance of clinical suspicion for mycosis fungoides in patients with widespread h...

Tetraploid-diploid mosaicism in humans is exceedingly rare. We present an 11-year-old boy with tetraploid-diploid mosaicism and coexistent hair hypopigmentation with skin hypo- and hyperpigmentation. This case expands the current literature as we are not aware of previous documentation of this unique combination of pigmentary anomalies.

Choroiditis is frequently found in patients with posterior segment inflammation associated with sarcoidosis. The most frequent pattern of choroidal involvement is areas of well circumscribed pre-equatorial choroidal depigmentation that become associated with retinal pigment epithelial (RPE) hyperor hypopigmentation with time.'" We present two patients with biopsy proved sarcoidosis in whom ther...

A 35-year-old woman who developed whitish macules on trunk and limbs at 12 years of age and observed a remarkable increase of the hypopigmentated lesions after her pregnancies at ages 29 and 32 years. Because of the highly characteristic clinical aspect and the light- and electron-microscopic histopathologic findings, we diagnosed progressive macular hypomelanosis (PMH). It is a nonscaly disord...

Fig. 1. (a) Localized hypertrichosis of the left arm restricted to the henna tattoo design. (b) Close-up view of hypertrichosis. complications such as permanent scarring, keloid formation, postinflammatory hypopigmentation (2), and sensitization by crossreactivity to chemically related substances (3). Transient hypertrichosis is a rare reaction that has seldom been reported after henna tattooin...

The author provides his perspective on resurfacing procedures in dark-skinned patients, advising a cautious approach to laser resurfacing. Laser complications in Fitzpatrick skin types III to VI, including hyperpigmentation, hypopigmentation, and scarring, are well documented. Unlike chemical peeling and dermabrasion, with laser resurfacing, preoperative treatment does not control postoperative...