this study was conducted to evaluate the hypoglycemic, hypocholesterolemic and antioxidant properties of mentha spicata (labiateae) leaves aqueous extract (msla) in alloxan-induced diabetic rats. in this study, hyperglycemia was induced in male rats by intraperitoneal injection of alloxan monohydrate (150 mg/kg). the aqueous extract of m. spicata was orally administered at a dose of 300 mg/kg b...

Background and Objective: Diabetes mellitus (DM) in long-term is associated with learning and memory decline. Metformin is an anti-diabetic drug with antioxidant and memory-improving effects. Thus, this research study was conducted to assess the effect of metformin on learning and memory in diabetic rats. Materials and Methods: In the present study, male Wistar rats (n=32) were randomly assign...

Patients with diabetes mellitus are likely to develop certain complication such as retinopathy, nephropathy and neuropathy as a result of oxidative stress and overwhelming free radicals. Treatment of diabetic patients with antioxidant may be of advantage in attenuating these complications. Oleuropein, the active constituent of olive leaf (Olea europaea), has been endowed with many beneficial an...

On administration of 2.5 g almond seed and its proportionate fractions, viz. 1.22 g defatted seed and 1.28 g oil to three groups of albino rabbits, they showed a definite hypoglycemic action during a two months study. The active factor seems to be a non oil fraction which is only partly soluble in ethyl ether.

Infusions of Citrullus colocynthis Schrad. (Cucurbitaceae) fruits are traditionally used as antidiabetic medication in Mediterranean countries, but to our knowledge, no studies have been undertaken so far to determine the possible mechanisms involved in the antidiabetic properties of the fruit. The present study was designed to investigate whether these fruits possess hypoglycemic effects. For...