This paper focuses on the implementation of a continuous control of the degree of articulation (hypo/hyperarticulation) in the framework of HMM-based speech synthesis. The adaptation of a neutral speech synthesizer to generate hypo and hyperarticulated speech using a limited amount of speech data is first studied. This is done using inter-speaker voice adaptation techniques, applied here to int...

1. Sodium and potassium transport rates were studied in normal human leucocytes exposed to iso-osmolal and hypo-osmolal extracellular fluid. 2. Hypo-osmolality of the extracellular fluid led to an increase in sodium influx and a decrease in potassium influx expressed as mmol h-’ kg-’ cell dry weight. The fall in potassium influx was smaller than the rise in sodium influx and was confined to the...

Amyloidosis cutis dyschromica (ACD) is a rare form of macular amyloidosis characterized by hypo and hyperpigmented macules. Here we described a 20 year old girl with diffuse hypo and hyperpigmentation since she was four years old. Five other members of her family are also involved. Biopsy of hyperpigmented lesions revealed increase of melanin in the basal layer, pigment incontinence and amorpho...

After moderate intracerebral hemorrhage (ICH), both hypothermia (HYPO) and constraint-induced movement therapy (CIMT) improve recovery and reduce the volume of brain injury. We tested the hypothesis that more severe ICH requires both cytoprotection and rehabilitation to significantly improve recovery. Rats were subjected to a unilateral striatal ICH via collagenase infusion. Rats remained normo...

The term hypochondriasis was first coined over 2000 years ago to describe a physical illness afflicting the hypochondrium. Subsequently the term was used for a variety of physical illnesses, until the 17th century when forms of melancholia were labelled as hypo chondriasis. Since then a very large number of psychiatric disorders have been given the term hypo chondriasis, for example, a form of ...

BACKGROUND The purpose of this paper is to study the spatial agreement between visual field defects and ultra-wide field (UWF) fundus autofluorescence (FAF) in patients with birdshot chorioretinopathy (BSCR). The study is a retrospective, cross-sectional analysis of a university uveitis practice. Eight (8) eyes of five (5) patients with BSCR were included. Inclusion criteria were ability to fix...

BACKGROUND Bivalirudin has emerged as a suitable alternative anticoagulant to unfractionated heparin and low-molecular-weight heparins during percutaneous coronary intervention (PCI) procedures in the management of coronary artery disease and acute coronary syndromes (ACS). In clinical trials, bivalirudin dosing was standardized, and activated clotting time (ACT) did not influence dosing adjust...

Introduction Mixed states, the co-occurrence of manic and depressive symptoms, were recognized described from time antiquity. DSM-5 first, DSM-5-TR after, introduced ‘’mixed features’’ specifier, defined by presence at least three non-overlapping opposite-pole symptoms during a syndromic depressive, hypomanic, or episode. Various manifestations, including irritability, distractibility, anxiety,...