Silver doped hydroxyapatite was prepared by the precipitation method, using the precursor of hydroxyapatite, CaCl2-0.5M and (NH4) 2HPO4-0.3M; silver sulfate (Ag2SO4) is added to the precursors in order to bring the ions of silver (Ag at 10%) in the structure of hydroxyapatite. The morphology, structure and composition of prepared samples were characterized by X-ray diffraction, the complex ther...

This study evaluates the cytotoxic and mutagenic effect of synthetic hydroxyapatite granules (source: School of Material and Mineral Resources Engineering, Universiti Sains Malaysia) in the bone marrow cells of mice. Mice are exposed to synthetic hydroxyapatite granules, the bone marrow cells are collected and observed for chromosome aberrations. No chromosome aberrations were noticed in the an...

Dietary components rich in polyphenols-for example, tea and red wine-are thought to cause tooth staining. In the present study, hydroxyapatite was used as a model of enamel for study of the influence of salivary proteins on the binding of different polyphenols to hydroxyapatite in vitro. Neither salivary protein pellicles nor salivary proteins in solution significantly altered the binding of th...

Fundamental to the processes of decalcification of or adhesion to mineralized tissues is the molecular interaction of acids with hydroxyapatite. This study was undertaken to chemically analyze the interaction of 1 mono-, 2 di-, 1 tri-, and 2 polycarboxylic acids with hydroxyapatite in an attempt to elucidate the underlying mechanism. Maleic, citric, and lactic acid decalcified hydroxyapatite, i...

PURPOSE To evaluate and compare clinically and radiographically use of hydroxyapatite crystals and 2% glutaraldehyde as a pulpotomy agent. METHOD Thirty deciduous molars were treated with pulpotomy using hydroxyapatite crystals and 2% glutaraldehyde. RESULTS Clinical and radiographic findings were observed at three months and six months. The success rate was found to be 100% clinically and ...

In a single-blind, randomised series of knee replacements in 116 patients, we used radiostereometric analysis (RSA) to measure micromotion in three types of tibial implant fixation for two years after knee replacement. We compared hydroxyapatite-augmented porous coating, porous coating, and cemented fixation of the same design of tibial component. At one to two years, porous-coated implants mig...

The specific adsorption of citric acid ions at hydroxyapatite interface was investigated by the means of radioisotope method (14C) as a function of citric acid ions concentration, NaCl concentration and pH. Application of the hydroxyapatite has become wide in the biomaterial field as the Ca10(OH)2(PO4)6 possess biocompatibility with human hard tissue. Hydroxyapatite was synthesized using three ...

the bone mineral consists of tiny hydroxyapatite (ha) crystals in the nanoregime. nanostructured ha is also expected to have better bioactivity than coarser crystals. this paper reports on the in vitro evaluation of bone like ha nanopowders. the prepared ha nanopowder was characterized for its phase purity, chemical homogeneity and bioactivity. fourier transform infrared (ft-ir) spectroscopy wa...

in a hydrothermal route devoted for synthesis of ca10(po4)6(oh)2 (ha) nanostructures, morphology can be controlled by experimental condition to form magical ha or nanostructured nanoparticles. in an intermediate condition, a novel nanostructure namely rose-like bundle of ha rod-likes was found, which is different from known ha nanostructures. the chemical synthesis of nanopowders under hydrothe...

The inhibitory and antimicrobial effects of silver particles have been known since ancient times. In the last few years, a major health problem has arisen due to pathogenic bacteria resistance to antimicrobial agents. The antibacterial activities of new materials including hydroxyapatite (HAp), silver-doped hydroxyapatite (Ag:HAp) and various types of antibiotics such as tetracycline (T-HAp and...