The publication in June 2007 of a White Paper in Multimodality Imaging [1] marked the recognition by both the European Society of Radiology (ESR) and the European Association of Nuclear Medicine (EANM) of the importance of coordinating future work practices to incorporate multimodality imaging. The white paper outlined principles and an approach to cooperation between both societies in response...

Semiconductor pixel detectors offer features for the detection of radiation which are interesting for particle physics detectors as well as for imaging e.g. in biomedical applications (radiography, autoradiography, protein crystallography) or in Xray astronomy. At the present time hybrid pixel detectors are technologically mastered to a large extent and large scale particle detectors are being ...

Hybrid imaging devices combining Positron-Emission-Tomography (PET) with Magnetic-Resonance-Imaging (MRI) have been shown to possess a great potential for small animal studies. Recently PET/MR systems have also been built for human applications. Here we present an evaluation of the first hybrid PET/MR device, which has the capabilities to perform simultaneous PET/MR acquisitions of the human br...

Hybrid nanoprobe specifically designed to use as a contrast agent targeting phagocytic cells in an animal model of ischemic stroke and imaging using MRI, intravital two-photon microscopy phase X-rays imaging.

Biology requires observations at multiple geometrical scales, a feature that is not typically offered by a single imaging modality. We developed a hybrid optical system that not only provides different contrast modes but also offers imaging at different geometrical scales, achieving uniquely broad resolution and a 1000-fold volume sampling increase compared to volumes scanned by optical microsc...

Silicon-based hybrid CMOS focal plane array technology offers many advantages needed for both ground-based and space imaging applications. These advantages include enhanced UV and NIR sensitivity, extensive on-chip readout capability, inherent radiation hardness, flexible imaging readout and the ability to provide extremely low noise at high video rates. For infrared imaging applications that i...

Introduction Myocardial perfusion and the status of the coronary arteries are the two major parameters for the characterization of coronary artery disease (CAD) and for guiding therapeutical interventions. It has been shown that hybrid imaging strategies to acquire both parameters such as SPECT with CT-angiography provide an added value for clinical decision making in the treatment of CAD[1]. T...

Nanotechnology offers outstanding potential for future biomedical applications. In particular, due to their unique characteristics, hybrid nanomaterials have recently been investigated as promising platforms for imaging and therapeutic applications. This class of nanoparticles can not only retain valuable features of both inorganic and organic moieties, but also provides the ability to systemat...

We have developed a novel, hybrid imaging modality, Transient Absorption Ultrasonic Microscopy (TAUM), which takes advantage of the optical nonlinearities afforded by transient absorption to achieve ultrahigh-resolution photoacoustic microscopy. The theoretical point spread function for TAUM is functionally equivalent to confocal and two-photon fluorescence microscopy, potentially enabling cell...