Hub covering location problem, Network design,   Single machine scheduling, Genetic algorithm,   Shuffled frog leaping algorithm   Hub location problems (HLP) are synthetic optimization problems that appears in telecommunication and transportation networks where nodes send and receive commodities (i.e., data transmissions, passengers transportation, express packages, postal deliveries, etc....

OBJECTIVES Regular and quality CD4 testing is essential to monitor disease progression in people living with HIV. In Haiti, most laboratories have limited infrastructure and financial resources and have relied on manual laboratory techniques. We report the successful implementation of a national specimen referral network to rapidly increase patient coverage with quality CD4 testing while at the...

of profitability, spatially spread demand, and intense competition have incited a trend to seek solutions through ICT and the Internet (3). One manifestation of this is an increase in collaboration among small to medium-sized LTL carriers. That is, small to medium-sized carriers have begun to develop strategies that exploit synergies (such as excess capacity, overlapping lanes, and facilities),...

This study formulates a two-objective model by individually minimizing shipping costs and inventory costs to decide whether to route a shipment through a hub or directly to its destination. First, shipping and inventory cost functions are formulated for a multi-port calling route. Shipping costs include capital and operating cost, fuel cost and port charge, while inventory costs include waiting...