By analyzing the problem of high pressure torsion (HPT) in the rigid plastic formulation, we show that the power hardening law of plastically deformed materials leads to self-similarity of HPT, admitting a simple mathematical description of the process. The analysis shows that the main parameters of HPT are proportional to β q , with β being the angle of the anvil rotation. The meaning of the p...

The research on structural features, microhardness distribution, and deformation features of Vit105 bulk metallic glass (BMG) before after high-pressure torsion (HPT), as well relaxing annealing, has been carried out. HPT n = 1 leads to an increase in free volume ?V, annealing a decrease ?V non-uniformity relative the initial state BMG. In BMG is uniformly distributed over surface, while materi...

Severe hyperparathyroidism can affect bone metabolism and be in the origine of multiple brown tumours (generalized osteitis fibrosa cystica). When associated with fibro-ossifying tumours of the jaw, it realizes a rare genetic syndrome referred as Hyperparathyroidism-jaw tumour HPT-JT. We report the case of a patient we treated for HPT-JT, and literature review.

Introduction: Chronic pain and pain sensitivity are complex traits with a variety of potential determinants. Although not yet fully elucidated, pain sensitivity and the risk for chronic pain are thought to be partly genetic. In our study, we attempt to further elucidate the genetic predisposition of pain sensitivity. Methods: In a total number of 3,795 participants from the Rotterdam study (a l...

The acute-phase protein haptoglobin (Hpt) binds apolipoprotein A-I (ApoA-I) and impairs its action on lecithin-cholesterol acyltransferase, an enzyme that plays a key role in reverse cholesterol transport. We have previously shown that an ApoA-I mimetic peptide, P2a, displaces Hpt from ApoA-I, restoring the enzyme activity in vitro. The aim of this study was to evaluate whether P2a displaces Hp...

PURPOSE This phase I study evaluated the effect of folate supplementation on the toxicity, tolerability, and pharmacokinetics of pemetrexed in patients with locally advanced or metastatic cancer. It also examined two different types of vitamin supplementation and whether the extent of prior myelosuppressive therapy affected pemetrexed tolerability. PATIENTS AND METHODS Patients received a 10-...

Aim: To measure and evaluate the effects of curriculum applied in Faculty Dentistry on psychomotor skills students.Design:The study was carried 416 volunteer students. Participants were put to "9-hole peg test" (9-HPT). The results classified by considering students' grades (1-5), gender (male female), test hand (dominant/non-dominant) variables. Methods: Although there is an improvement 9-HPT ...

The study aimed to evaluate the diagnostic accuracy of intraoperative intact parathyroid hormone (IO-iPTH) in patients with secondary hyperparathyroidism (HPT). The cut-off for IO-iPTH monitoring remains unknown. This was a single-center retrospective review of 226 consecutive patients (107 males and 119 females) who underwent parathyroidectomy data for secondary HPT between May 2010 and March ...

For the first time, tribological behaviour of 316 L stainless steel (316 SS) additively manufactured via laser powder bed fusion (L-PBF) with ultrafine- and nano-grains obtained from high-pressure torsion (HPT) processing has been investigated. The pin-on-disk dry sliding wear test results demonstrate enhancement performance after HPT processing, as indicated by consistently lower coefficient f...