نتایج جستجو برای: homeostasis model assessment of insulin resistance

تعداد نتایج: 21465947  

Journal: :middle east journal of digestive diseases 0
shahin merat s yarahmadi s tahaghoghi z alizadeh n sedighi n mansournia

â  â  background a substantial proportion of the mortality in patients with type 2 diabetes mellitus (t2dm) is related to non-alcoholic fatty liver disease (nafld) and its complications. insulin resistance is a major etiologic factor for the development of fatty liver. we aimed to study the prevalence of nafld among t2dm patients and its relation to insulin resistance. methods patients with t2d...

اقتصادی, شهریار, حسینی, آغا فاطمه, حقیقت, ندا, حیدری, ایرج, وفا, محمدرضا,

 Background: Tocotrienolswhich were neglected in the past, today get attentions due to their antioxidant and none-antioxidant activity. The purpose of this study was to determine the effects of 8 weeks consumption of 15 ml T3 enriched canola oil (200mg/day T3) on glycemic controlandoxidative stress in type 2 diabetic patients. Methods: Thisclinical trial was conducted on 50 patients ...

Journal: :Stroke 2009
Takao Urabe Hirotaka Watada Yasuyuki Okuma Ryota Tanaka Yuji Ueno Nobukazu Miyamoto Yasutaka Tanaka Nobutaka Hattori Ryuzo Kawamori

BACKGROUND AND PURPOSE The purpose was to assess the prevalence of disorders of glucose metabolism and insulin resistance in Japanese ischemic stroke patients with no history of diabetes by performing 75-gram oral glucose tolerance test (OGTT). METHODS We recruited 427 ischemic stroke patients (atherothrombotic infarction, n=220; lacunar infarction, n=125; cardioembolic infarction, n=82). OGT...

2011
Philip J. Barter

Background—High-density lipoproteins have antidiabetic properties in vitro. Furthermore, elevated high-density lipoprotein levels accompanying a genetic deficiency of cholesteryl ester transfer protein are associated with decreased levels of plasma glucose. We now investigate effects on glucose homeostasis of inhibiting cholesteryl ester transfer protein with torcetrapib. Methods and Results—A ...

2012
Jin Ook Chung Dong Hyeok Cho Dong Jin Chung Min Young Chung

BACKGROUND/AIMS We investigated the associations among body mass index (BMI), insulin resistance, and β-cell function in Korean patients newly presenting with type 2 diabetes. METHODS In total, 132 patients with new-onset type 2 diabetes mellitus were investigated. A standard 75-g oral glucose tolerance test was performed, and the indices of insulin secretion and insulin resistance were calcu...

2013
A H Sam M Busbridge A Amin L Webber D White S Franks N M Martin M Sleeth N A Ismail N Mat Daud D Papamargaritis C W Le Roux R S Chapman G Frost S R Bloom K G Murphy

AIM Increased body iron is associated with insulin resistance. Hepcidin is the key hormone that negatively regulates iron homeostasis. We hypothesized that individuals with insulin resistance have inadequate hepcidin levels for their iron load. METHODS Serum concentrations of the active form of hepcidin (hepcidin-25) and hepcidin:ferritin ratio were evaluated in participants with Type 2 diabe...

Journal: :Oman medical journal 2010
Rayah S Baban Khawla A K Kasar Isam N Al-Karawi

OBJECTIVES To identify the fasting glucose/leptin ratio as a new simple method for the detection of insulin resistance in Iraqi diabetes mellitus patients, and to examine its usefulness as a new marker for insulin resistance. METHODS A case control study conducted at the National Diabetes Center, College of Medicine at Al-Mustansiryia University from 1 August 2008 to 30 January 2010. An enzym...

اصلانی مغانجوقی, سجاد, صفرزاده, علیرضا, صیقل, حسن, طالبی گرگانی, الهه, فتحی, رزیتا,

Background: Visfatin is an adipokine secreted from visceral adipose tissue and involved in glucose homeostasis. The aim of the present study was to investigate the effect of eight-week resistance training on plasma visfatin levels and its relation to insulin resistance in insulin-resistant male rats. Methods: In this experimental study twenty-four Wistar male rats­ (220±20 gr) were acclimati...

2015
Olga Barbarash Olga Gruzdeva Evgenya Uchasova Ekaterina Belik Yulia Dyleva Victoria Karetnikova

BACKGROUND Dyslipidemia is a key factor determining the development of both myocardial infarction (MI) and its subsequent complications. Dyslipidemia is associated with endothelial dysfunction, activation of inflammation, thrombogenesis, and formation of insulin resistance. Statin therapy is thought to be effective for primary and secondary prevention of complications associated with atheroscle...

2016
Yu-Xiang Yan Huan-Bo Xiao Si-Si Wang Jing Zhao Yan He Wei Wang Jing Dong

BACKGROUND Chronic stress may facilitate the development of metabolic diseases. Insulin resistance is present long before the clinical manifestations of individual metabolic abnormalities. To explore whether chronic stress is an independent risk factor of insulin resistance, we investigated the relationship between the stress system, selected parameters of energy homeostasis, and insulin resist...

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