Covid beschert den großen Pharmaunternehmen stagnierende Umsätze und Erträge. Österreichs spielen im Konzert der Großen eine kleine, aber vernehmbare Rolle.

This article examines the behavior of consumer price index in Ukraine for period from January 2010 to September 2020. The characteristics initial time series, analysis autocorrelation functions made it possible reveal tendency their development and presence annual seasonality. To model forecast next months, two types models were used: additive ARIMA*ARIMAS model, better known as Box-Jenkins exp...

• Traditional approaches, including Box–Jenkins autoregressive integrated moving average (ARIMA) model, autoregressive and moving average with exogenous variables (ARMAX) model, seasonal autoregressive integrated moving average (SARIMA) model, exponential smoothing models [including Holt–Winters model (HW) and seasonal Holt and Winters’ linear exponential smoothing (SHW)], state space/Kalman fi...

In this BMJ Confidential (BMJ 2014;349:g7093, doi:10.1136/ bmj.g7093) Kim Holt said that, if she could be invisible for 24 hours, she would like to attend the discussions at the Department of Health on the Francis review. In editing the piece, we mistakenly referred to this as being the Francis inquiry into the Mid Staffordshire Foundation Trust, which was chaired by Robert Francis and publishe...

In the Beverton Holt difference equation of population biology with intrinsic growth parameter above its critical value, any initial non-zero population will approach an asymptotically stable fixed point, the carrying capacity of the environment. When this carrying capacity is allowed to vary periodically it is known that there is a globally asymptotically stable periodic solution and the avera...

Holt-Oram syndrome is clinically characterized by morphological abnormalities of the upper limbs and congenital cardiac defects. Although the disease is congenital, the diagnosis may only be made later in life. It is a rare autosomal dominant disorder, caused by a mutation in the TBX5 gene located on chromosome 12, but sporadic cases have also been reported. We describe the case of a 75-year-ol...

Introduction Holt & Oram (1960) linked various skeletal abnormalities with congenital heart disease in four generations of a family. In particular, malformations of the hands were associated with atrial septal defect (secundum type) and bizarre arrhythmias. In 1961, McKusick described a similar syndrome in a mother and daughter and suggested the term 'atrio-digital dysplasia'. Harris & Osborne ...

Institute of Mathematics of the Academy of Sciences of the Czech Republic provides access to digitized documents strictly for personal use. Each copy of any part of this document must contain these Terms of use. This paper has been digitized, optimized for electronic delivery and stamped with digital signature within the project DML-CZ: The Czech Digital Mathematics Library The paper suggests a...

Holt and Klee have recently shown that every (generic) LP orientation of the graph of a d-polytope satisfies a directed version of the d-connectivity property, i.e. there are d internally disjoint directed paths from a unique source to a unique sink. We introduce two new classes HK and HK* of oriented matroids (OMs) by enforcing this property and its dual interpretation in terms of line shellin...