Faithful chromosome segregation in meiosis is crucial to form viable, healthy offspring and in most species, it requires programmed recombination between homologous chromosomes. In fission yeast, meiotic recombination is initiated by Rec12 (Spo11 homolog) and generates single Holliday junction (HJ) intermediates, which are resolved by the Mus81-Eme1 endonuclease to generate crossovers and there...

Monitoring surface albedo at medium-to-fine resolution (<100 m) has become increasingly important for medium-to-fine scale applications and coarse-resolution data evaluation. This paper presents a method for estimating surface albedo directly using top-of-atmosphere reflectance. This is the first attempt to derive surface albedo for both snow-free and snow-covered conditions from medium-resolut...

Holliday junction (HJ) resolving enzyme RecU is involved in DNA repair and recombination. We have determined the crystal structure of inactive mutant (D88N) of RecU from Bacillus subtilis in complex with a 12 base palindromic DNA fragment at a resolution of 3.2 Å. This structure shows the stalk region and the essential N-terminal region (NTR) previously unseen in our DNA unbound structure. The ...

Citation: Liu J, Ciarochi J, Calhoun VD, Paulsen JS, Bockholt HJ, Johnson HJ, Long JD, Lin D, Espinoza FA, Misiura MB, Caprihan A, Turner JA and PREDICT-HD Investigators and Coordinators of the Huntington Study Group (2018) Genetics Modulate Gray Matter Variation Beyond Disease Burden in Prodromal Huntington’s Disease. Front. Neurol. 9:190. doi: 10.3389/fneur.2018.00190 genetics Modulate gray M...

In standard notation, let {H1,H2, · · · ,Hm} and {A1, A2, · · · , An} be two distinct partitions of the sample space, or equivalently two sets of events satisfying three properties: (i) each event is non-void, (ii) events in the same set are mutually exclusive (i.e. P (Hj ∪Hk) = P (Hj)+P (Hk) for j 6= k), and (iii) each set is collectively exhaustive, (i.e. P (∪i=1Hj) = 1). The Bayes formula in...

PURPOSE To determine the step count accuracy of three pedometers and one accelerometer in pregnant women during treadmill walking. METHODS Participants were 30 women in the second or third trimester (20-34 wk) who were screened for pregnancy-related risk factors. Each participant was fitted with a belt containing three physical activity monitors: Yamax Digiwalker SW-200 (DW), New Lifestyles N...

Some bacteria can carry out anaerobic respiration by depositing electrons on external materials, such as electrodes, thereby creating an electrical current. Into the anode chamber of microbial fuel cells (MFCs) having abiotic air-cathodes we inoculated microorganisms cultured from a magnetic particle-enriched portion of a marine tidal sediment, reasoning that since some external electron accept...

The limitations of satellite data acquisition mean that there is a lack of satellite data with high spatial and temporal resolutions for environmental process monitoring. In this study, we address this problem by applying the Enhanced Spatial and Temporal Adaptive Reflectance Fusion Model (ESTARFM) and the Spatial and Temporal Data Fusion Approach (STDFA) to combine Huanjing satellite charge co...

Protein-DNA interactions are essential for gene maintenance, replication, and expression. Characterizing how proteins interact with and change the structure of DNA is crucial in elucidating the mechanisms of protein function. Here, we present a novel and generalizable method of using engineered DNA Holliday junctions (HJs) that contain specific protein-recognition sequences to report protein-DN...

In this paper, we will present a Pc1D numerical simulation for heterojunction (HJ) silicon solar cells, and discuss their possibilities and limitations. By means of modeling and numerical computer simulation, the influence of emitter-layer/intrinsic-layer/crystalline-Si heterostructures with different thickness and crystallinity on the solar cell performance is investigated and compared with ho...