Currently, the laboratory diagnostic tests available for HIV-1 viral infection are mainly based on serological testing which relies enzyme-linked immunosorbent assay (ELISA) blood HIV antigen detection and reverse transcription polymerase chain reaction (RT-PCR) specific RNA sequence identification. However, these methods expensive time-consuming, suffer from false positive and/or negative resu...

HIV is considered a public health problem in the world, especially Brazil, where about 194,000 people have been infected with virus last 10 years country. In addition to physical problems that infection imposes on HIV-positive individuals, social and institutional end up being major barrier lives of these such as stigma prejudice, which segregate exclude them from life. Objective: make critical...

Individuals infected with human immunodeficiency virus type-1 (HIV-1) show metabolic alterations of CD4+ T cells through unclear mechanisms undefined consequences. We analyzed the transcriptome from patients HIV-1 and revealed that elevated oxidative phosphorylation (OXPHOS) pathway is associated poor outcomes. Inhibition OXPHOS by US Food Drug Administration–approved drug metformin, which targ...

The work is based on a retrospective analysis of literature data covering tactical approaches, indications and contraindications, treatment results in patients with HIV infection who underwent organ transplantation. the most up-to-date publications transplantation HIV-infected Russian Federation abroad has been carried out. criteria under which an patient favorable are noted. Cases subsequent d...

In this paper, we develop a mathematical model to examine the transmission dynamics of curable malaria, curable mTB and non-curable HIV/AIDS and their co-infection. The size of population has been taken as varying due to the emigration of susceptible population. The total population is divided into five subclasses as susceptible, malaria infected, mTB infected, HIV infection and AIDS by assumin...

objective: despite sensitive antibody based blood donor screening, infection can be transmitted during window period. therefore sensetive methods bosed on nucleic acid tests (nats) have been considered. the aim of this project was to design a more sensitive method for detection of pcr products and diagnosis of hiv-1/hcv co-infection accurately. materials and methods: after designing specific p...

Background: HBV and HCV infection, have been found to worsen the health of PLWAS, thereby impairing treatments management. HIV, HBV, are transmitted through similar routes hence presence infection with any them could be a risk factor for others. Objective: Determine prevalence HBV/HCV co-infection in persons HIV. Method: This was serological study For Hepatitis B surface antigen investigated an...

patients and methods in the present cross-sectional study, 109 patients with established hiv infection, who visited a governmental and referral center for hiv screening in tehran (tehran west health center (twhc)) between may 2014 and july 2015 were enrolled according to the convenience sample strategy. after peripheral blood collection, isolation of plasma and peripheral blood mononuclear cell...