Nanosilver has recently been recognized as an antimicrobial agent. Although this nanoparticlecan be used in medical applications but its dermal and systemic toxicity via dermal exposure hasnot been completely determined yet. The aim in this study was to investigate the potential dermaltoxicity of Nanosilver in subchronic method. Before the colloidal silver nanoparticle toxicityevaluation, their...

the modern surgical endodontic treatment is a safe and predictable procedure with high success rate. however, several factors can retard or impede the proper healing process. use of a high speed handpiece during hard tissues management (osteotomy and apical resection) can potentially be one of these factors. formation of metallic debris from the surgical diamond burs, production of necrotic loc...

Background: Morbid obesity is a multifactorial disease that increasingly is being treated by surgery. Aim: To evaluate gastric histopathological changes in obese, and to compare with patients who underwent gastrojejunal bypass and the jejunal mucosa after the surgery. Methods: This is an observational study performed at a tertiary public hospital, evaluating endoscopic biopsies from 36 pre...

Primary atrophic rhinitis is a progressive chronic nasal disease and histopathologically characterized by squamous metaplasia and two characteristic types of vascular involvement (type I and type II). Despite its chronicity and squamous transformation, nothing is known about the occurrence of malignancy in atrophic rhinitis. The present work was undertaken to study the histopathological charact...

Effect of topiramate, an antiepileptic drug, on the development of conceptus and its safety during pregnancy has been investigated in experimental rats. Rats were treated with topiramate dissolved in tap water in the doses of 40. 100 and 200 mg/kg body weight from day 9 to 12 of gestation through oral route. Fetuses along with placenta were collected for examination on day 21 of gestation after...

Histological evidence of Plasmodium in the placenta is indicative of placental malaria, a condition associated with severe outcomes for mother and child. Histological lesions found in placentas from Plasmodium-exposed women include syncytial knotting, syncytial rupture, thickening of the placental barrier, necrosis of villous tissue and intervillositis. These histological changes have been asso...

Between 1948 and 1950, Dalldorf and Sickles (1948), Dalldorf and others (1949), Dalldorf (1950), and Sickles and Dalldorf (1949) reported a previously unidentified virus in the faeces of children with the symptoms of acute anterior poliomyelitis. This virus has been named Coxsackie or C.-virus, and many authors (Magnus, 1949; Kaplan and Melnick, 1951; Melnick, 1947, 1950a, 1950b; Melnick and Go...

BACKGROUND The exchange of substances between mother and fetus via the placenta plays a vital role during development. A number of developmental disorders in the fetus and placenta are observed during diabetic pregnancies. Diabetes, together with placental apoptosis, can lead to developmental and functional disorders. AIMS Histological, ultrastructural and apoptotic changes were investigated ...

The aim of this study was to determine the long term histopathologic changes in tracheal mucosa after a total laryngectomy , and to find out the relationship between the progression of histopathologic changes in tracheal mucosa and the duration of breathing through the tracheostomy. Tracheal mucosal biopsies were taken from a total of 35 patients, of both sexes, who underwent a total laryngecto...

Cypermethrin was administered to Heteropneustes fossilis in chronic concentration to determine lesion of liver as indicators of tissue damage. The cypermethrin dose used was 1/4 of 96 hr LC50. Histopathological changes in liver ranged from vacuolization, necrosis, fibrosis of perivascular region and disposition of yellow brown grains at different time of exposure viz; 20th, 30th, 40th and 60th ...