PURPOSE to evaluate the agreement between histopathologic diagnoses of breast lesions made by general pathologists and by a specialist in breast pathology. METHODS a cohort retrospective study comparing histopathologic diagnoses of 329 cases of breast lesions received in consultation for a second opinion was carried out. The material received for consultation included slides (152 cases), para...

liver lesion is a common condition, which often detect incidentally. a large proportion of liver masses can be diagnosed by progression in imaging modalities. although, definite diagnosis of liver mass's nature can be made by biopsy of lesion and histopathologic examination, but with imaging findings, we can approach to the diagnosis. in this study, we review many valuable articles and scientif...

Primary lymphedema (PLE) is an uncommon diagnosis in veterinary medicine, with most of the previously described cases showing lower limb edema associated a guarded long-term prognosis. To authors’ knowledge, this case report describes first localized unilaterally to facial region one-year-old German Shorthair Pointer, which indirect CT-lymphography, combined histopathologic examination skin, re...

PURPOSE To describe a case of severe corneal granular dystrophy with clinicopathologic and molecular genetic findings. METHODS The DNAs of a 53-year-old male patient suffering from corneal granular dystrophy and nonaffected family members were analyzed by molecular genetic methods. Clinical features, and histopathologic and immunohistochemical findings from the penetrating keratoplasty specim...

Numerous distinct neoplasms are encountered at the anterior cranial base. Management of these primary tumors and their locoregional recurrences are dictated by the histopathologic diagnosis. We present two unusual cases of extra-axial anterior cranial base malignancies with locoregional recurrence where the recurrent tumor encountered was of a distinct histopathologic type. While rare, this rep...

Diffuse large B-cell lymphoma (DLBCL) of the heart accounts for only 1% primary cardiac tumors. Histopathologic examination becomes key diagnosis and immunohistochemical evaluation non-Hodgkin (NHL) subtype determination is able to predict disease progression therapeutical modality. Case description: 70-year-old man complained shortness breath. Echocardiographic revealed mass occupied left atri...

Background: Skin adnexal tumors are a spectrum of benign and malignant that differentiate toward or arise from the unit skin. These rare pose challenge in diagnosis, often, discrepancy is seen between clinical histopathological diagnosis. Materials methods: This single institutional study was carried out among 36 patients who presented with swelling. An initial diagnosis considered based on his...

Sarcoidosis is multi organ disease with cutaneous manifestation in 20%-35% patients. Cutaneous sarcoidosis has variable manifestations that make it difficult to diagnose. So clinical, histopathologic and laboratory evaluation is needed for diagnosis. Most of cutaneous lesions presents as nodul, maculopapule and plaque. Morpheaform lesion is a rare presentation of cutaneous sarcoidosis. This cas...

Here we provide a brief description of our program to improve diagnostic accuracy in cases with phenotypically similar presentations that are due to distinct histopathologic abnormalities. We propose a staged approach to diagnosis, beginning with a screening assessment of specific, quantitative neuropsychological measures, and followed by assessments of imaging and biofluid biomarkers. Our goal...

Oral cavity is commonly affected by number of lichenoid lesions, whose clinical and histopathologic features overlap due to the presence of inflammatory cells in connective tissue. Segregation of these lichenoid lesions is mandatory as each may embody a distinct disease entity in terms of cause, diagnosis and prognosis. The literature discussed in the article is an attempt to segregate individu...