BACKGROUND Histologic image analysis plays an important role in cancer diagnosis. It describes the structure of the body tissues and abnormal structure gives the suspicion of the cancer or some other diseases. Observing the structural changes of these chaotic textures from the human eye is challenging process. However, the challenge can be defeat by forming mathematical descriptor to represent ...

IgA nephropathy exhibits considerable histologic variability, ranging from normal histology to diffuse proliferative and crescentic glomerulonephritis (GN), although the majority of cases are characterized by focal or diffuse, predominantly mesangial proliferative GN. A number of different histologic classifications have been devised for IgA nephropathy, focusing on glomerular changes, tubulo-i...

BACKGROUND & AIMS Patients with primary sclerosing cholangitis (PSC) and ulcerative colitis (UC) have a high risk of colonic neoplasia. Neoplasia frequently develops in the proximal colon in patients with PSC. Histologic inflammation is an independent risk factor for the development of neoplasia; we investigated whether patients with UC and PSC have more subclinical disease activity than patien...

Syringocystadenocarcinoma papilliferum (SCACP) is a very rare cutaneous adnexal neoplasm. SCACP presents histologic variability, and it is difficult to establish the diagnosis from a punch biopsy. SCACP has an overall configuration similar to that of syringocystadenoma papilliferum (SCAP). When we diagnose SCACP, the histologic features of SCAP can be contributing and immunohistochemical staini...

Introduction: Overexpression of Human Epidermal Growth factor Receptor-2 (HER-2) is one of the most important prognostic and predictive factors of breast cancer, observed in 25% - 30% of breast carcinoma patients leading to poor prognosis and feasible anti HER-2 antibody drugs. The objective of this study was to evaluate the HER-2 frequency in target population and its correlat...

STUDY OBJECTIVE To determine the diagnostic yield of histologic specimens obtained by postmortem transbronchial biopsy (TBB) in patients with acute respiratory failure requiring mechanical ventilation. DESIGN Standard postmortem histologic examination of lung tissue specimens. SETTING An urban university-affiliated hospital. PATIENTS OR PARTICIPANTS Thirty patients with diffuse pulmonary ...

Background and Objectives: Breast cancer is the most common malignancy among women in the world. The aim of this study was to assess estrogen receptor (ER), progesterone receptor (PR) and HER-2/neu of infiltrating ductal carcinoma (IDC) with tumor size, histologic grade, lymph node metastasis and age. Methods: This study was carried out on 300 tissue blocks ofpatients with ID...

we have studied the patients who had a neck mass on presentation in five medical centers of tehran univ. of medical sciences (infectious disease department, ent department, dentistry faculty, cancer institute) during a period of 14 months. sixty patients, 20 women and 40 men, were eligible for our study. all patients underwent clinical and paraclinical work up and finally had histologic diagnos...

BACKGROUND The role of histology in the targeted management of nonsmall cell lung cancer (NSCLC) has garnered renewed attention in recent years. We provide contemporary population-based estimates of survival and an assessment of important prognostic factors in stage IV NSCLC by major histologic subtype. METHODS Using data from the Surveillance, Epidemiology and End Results (SEER) Program, we ...