Pheochromocytoma in elderly people is a very rare disease and surgical removal the only cure. Here we present an 81-year-old gentleman with multiple co morbidities left adrenal incidentaloma. He was diagnosed to have pheochromocytoma biochemical evaluation. underwent laparoscopic adrenalectomy after prolonged preparation alpha beta blockers. This second oldest patient histo-pathological diagnos...

Cellular senescence contributes to organismal development, aging, and diverse pathologies, yet available assays to detect senescent cells remain unsatisfactory. Here, we designed and synthesized a lipophilic, biotin-linked Sudan Black B (SBB) analogue suitable for sensitive and specific, antibody-enhanced detection of lipofuscin-containing senescent cells in any biological material. This new hy...

Iron overload has been measured in 100 hepatic biopsies by three different methods: (i) biochemical assay of the liver iron concentration (LIC), (ii) histological grading (HISTO) and (iii) automated image analysis with a Leitz Texture Analysis System by estimating two parameters, (a) the total iron area (TIA) and (b) the first grey level step (FGLS) at which the iron is detected. Image analysis...

Background: The mucosa of the oral cavity is very important from the dermatologist’s point of view as it originates from the ectoderm. The structure and the lining of the oral cavity has importance in the diagnosis of oral as well as systemic diseases, as it is the site of various isolated mucosal lesions as well as mucosal lesions of systemic diseases. The physical examination is completed by ...

Meckel-Gruber syndrome is a rare autosomal recessive lethal malformation characterised by typical manifestations of occipital encephalocele, bilateral polycystic kidneys and post axial polydactyly. But clinically unsuspected or atypical features may be discovered at autopsy or pathological study. One such rare case, diagnosed by ultrasound scan at 21weeks of gestation was terminated and present...

Small cell neuroendocrine carcinoma of the paranasal sinuses was first described by Raychowdhuri in 1965 [10], drawing attention to the resemblance between the lesion and pulmonary small cell carcinoma. We report a case of small cell neuroendocrine carcinoma of ethmoid sinus with invasion of the upper medial aspect of right maxillary sinus and medial aspect of right orbit. The optimal treatment...