نتایج جستجو برای: high risk breast cancer
تعداد نتایج: 3546580 فیلتر نتایج به سال:
Objective: The aim of the present study was to investigate risk factors for breast cancer in women under 40 years.during recent 10 years(1998-2007) Materials and Methods: The study was a descriptive case control analysis one in Imam khomeiny hospital.Cases were 312 women under40 years with histologically confirmed, breast cancer, and controls were 312 women with same age Presenting to hospi...
BACKGROUND Benign breast disease and high breast density are prevalent, strong risk factors for breast cancer. Women with both risk factors may be at very high risk. METHODS We included 42818 women participating in the Breast Cancer Surveillance Consortium who had no prior diagnosis of breast cancer and had undergone at least one benign breast biopsy and mammogram; 1359 women developed incide...
background: clinical experiences have revealed that patients with breast cancer experience various sexual problems following their treatment. breast cancer negatively impacts the sexual life of the afflicted couples, and as a traumatic event can influence women’s psychosexual functioning and intimate relationship. this review focuses on sexuality after breast cancer and on a growing need for bi...
Objective(s):Cytochrome P-450 1A1 is an important enzyme in the first phase of the metabolism of some carcinogens such as polycyclic aromatic hydrocarbons (PAHs), as well as estrogen. The present study evaluates the existence of CYP1A1 polymorphism in a number of breast cancer samples. Materials and Methods: One hundred breast cancer patients and the same number of healthy controls were analyz...
Abstract Background and objectives: Breast cancer is the most prevalent one in women. Some of the common causative factors are genetic background, nutritional and environmental factors. Viruses are believed as a risk factor in this cancer, too. Recent studies reported that Human Papillomaviruses can be one of the possible risk factors of breast cancer. This study focused on investigation of the...
Background and purpose: Single-nucleotide polymorphisms (SNPs) within miRNA genes may be related with risk of cancer. A main SNP in the pre-miR-27a (rs895819) with an A to G variation was earlier identified. In this study, we aimed to explore any association between SNP rs895819 in the miR-27a gene and breast cancer susceptibility. Materials and methods: This case-control study included 120 br...
Risk of Breast cancer in women with palpable breast cysts
Background: Breast cancer is one of the most common worldwide malignancies among women. Biological data suggest that damage induced by endogenous and exogenous factors affects the integrity of DNA and associated with susceptibility to breast cancer. Single nucleotide polymorphisms (SNPs) in DNA repair genes can associated with differences in the repair efficiency of DNA damage and may affect br...
Status of FAS and FAS Ligand Gene Polymorphisms in Patients wi th Breast Cancer in Northeastern IRAN
Background: The First apoptosis signal (FAS) and First apoptosis signal ligand (FASL) genes initiate the apoptosis pathway, playing a central role in the tumor growth and metastasis. Gene polymorphisms including -1377 G/A in the promoter region of FAS and -844 C/T in the promoter region of FASL have shown to change the transcription activities of these genes. Methods: In this study we evalua...
background: dna methyltransferase-3b (dnmt3b) is an important enzyme responsible for maintaining the dna methylation pattern in eukaryotic cells. in this study we have investigated the correlation between the 46359c→t polymorphism in the dnmt3b gene and the risk of breast cancer incidence among sporadic breast cancer patients in fars province, southern iran. methods: in this case-control study,...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید