BACKGROUND Antibiotics are frequently used to treat hidradenitis suppurativa (HS); however, few data on their efficacy are available. OBJECTIVE To evaluate the efficacy of a combination of systemic clindamycin (300 mg twice daily) and rifampicin (600 mg daily) in the treatment of patients with severe HS. METHODS Patients (n = 116) who received this combination were studied retrospectively. ...

BACKGROUND Oral isotretinoin has been used to treat mild to severe hidradenitis suppurativa (HS). OBJECTIVE We reviewed the results of low-dose isotretinoin for 4 to 6 months in the treatment of 68 patients with HS. METHODS This is a retrospective study. Data are presented in terms of response rate, long-term follow-up, and the relation between response rate and severity. RESULTS In 16 pa...

s, american academy of dermatology, 64th annual meeting, march 3–7, 2006 san francisco, CA. J Am Acad Dermatol. 2006 Mar; 54(3):AB58. IM Ig as a treatment for suppurative disease. 2005 POSTER HS treated with Dapsone Gupta.pdf Gupta S, Taibjee S, Lewis H. Hidradenitis suppurativa treated with dapsone, a case series of six patients, BRISTOL CUP POSTER. Br J Dermatol. 2005 June; 153(S1):20-51. Six...

The pathophysiology of hidradenitis suppurativa (HS) is not well understood. Some of our knowledge comes from clinical and epidemiological observations, along with studies of the histopathology and immunohistochemistry of affected skin. More recently, cutaneous molecular studies and transcriptomic analyses have provided additional information regarding inflammatory processes. The chronic cutane...

A 9-year-old girl developed hidradenitis suppurativa 3 months after the first signs of adrenarche. Such a close temporal relationship is consistent with the hypothesis that the disease is androgen dependent. Less than 2% of patients have onset of the disease before the age of 11 years. The exceptionally early age of onset in our patient may be partly explained by the fact that she had an early ...

Dermatology nurses and other health care professionals may sometimes fail to appreciate and recognize the physical and emotional challenges faced by patients with a particular chronic dermatologic disease or condition. To better bring patients’ feelings and perceptions into focus, the Dermatology Nursing Editorial Board is excited to introduce a new series, “Patients’ Perspectives: Living With....