One of the greatest challenges in the treatment of pancreatic cancer remains its inherent lack of beneficial response to cytotoxic chemotherapy. According to the encyclopedic knowledge on herbal medicine regimen and clinical experience accumulated for centuries, traditional Chinese medicine can provide new avenues for alternative treatments of pancreatic diseases. Chinese herbal extracts have b...

The increase of herbal medicine use led many scientists to contribute to the research in this field. Also a few pharmacologists, after an initial phase of correct criticisms, today recognize the possibility of investigating the scientific value of medicinal products composed essentially of vegetable extracts. However, it is logical to pose the questions: (i) is there a role for the pharmacologi...

aims: in our previous studies, we showed the inhibitory effects of punica granatum l. flower and rhus coriaria l. fruit water extracts on dental plaque accumulation by several bacteria, especially streptococcus mutans (s. mutans), on orthodontic wire by in vitro assays. in this study, the anti-cariogenic properties of the extracts were evaluated by assessing their effects on expression of glyco...

With recent developments in science and technology, there is a greater awareness of heavy metals such as Pb, Cr, Cu, Ni, As, K, Na and Ca, which are present in some TCMs. Therefore the analysis of both toxic and benefi cial heavy metals is crucial in quality control of TCMs, and regulations have been implemented to restrict their levels. In order to enhance TCM safety and management, the Chines...

herbal medicines can be used as the potential sources of anti-oxidative compounds to help the treatment of diseases associated to oxidative stress. in this paper, the ferric reducing antioxidant power (frap) activity of four lamiaceae herbal extracts, which traditionally applied in oxidative stress related diseases, has been evaluated and total phenolics contents of these extracts determined by...

The growing market of herbal remedies worldwide could pose severe problems to consumers’ health due to the possible presence of potentially harmful, undeclared synthetic substances or analogues of prescription drugs. The present work shows a simple but effective approach to unequivocally identify synthetic anorectic compounds in allegedly ‘natural’ herbal extracts, by exploiting Q-TOF LC/MS tec...

Background: Pathological conditions, including ischemic stroke, are associated with severe Endoplasmic Reticulum (ER) stress that induces apoptosis and cell death. Herbal medicines are natural treatments with few side effects in such situations. Objectives: In the present study, we examined the probable neuroprotective effects of Viola spathulata, Lamium album, and Urtica dioica on splicing of...

Undeclared synthetic substances or analogues of prescription drugs in herbal remedies can cause potential harm. The present work shows a simple but effective approach to unequivocally identify synthetic anorectic compounds in what is considered ‘natural’ herbal extracts, by exploiting Q-TOF LC/MS technology, with the help of the Agilent’s Forensic Accurate Mass Li-brary (Forensic PCDL AM), Agil...

Undeclared synthetic substances or analogues of prescription drugs in herbal remedies can cause potential harm. The present work shows a simple but effective approach to unequivocally identify synthetic anorectic compounds in what is considered ‘natural’ herbal extracts, by exploiting Q-TOF LC/MS technology, with the help of the Agilent’s Forensic Accurate Mass Li-brary (Forensic PCDL AM), Agil...