objective: the present study was undertaken to evaluate anti-depressant activity of myristica fragrans(ms). materials and methods: male wistar rats were subjected to imipramine and herbal extract ofms for their antidepressant activity using forced swimming test (fst), reserpine reversal test (rrt), haloperidol-induced catalepsy (hic), and pentobarbitone sleeping time (pst). results: administrat...

cancer is a major cause of death worldwide and causes serious problems in human life. it is developed by uncontrolled growth of a cell or a group of cells. there are many difficulties in treatment of cancer and many researchers are involved in investigating for effective drugs to treat the disease. caryophyllaceae is a large family of about 86 genera and 2200 herbaceous or subshrub species. the...

nano dithiocarbamate (dtc) complex have been prepared by reaction between dithiocarbamate and metal salt under ultrasound irradiation. reaction conditions such as the ligand dtc and phennantroline concentration, aging time and the ultrasonic device power show important roles in the size, morphology and growth process of the final products. the dithiocarbamate complex nanoparticles have been pre...

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the uses of non-steroidal anti-inflammatory drugs (nsaids) are limited by a variety of side effects. so research on preparing new analgesic agents is important. according to some reports about the analgesic activity of hydrazide and hydrazine derivatives a new series of these compounds were synthesized in order to obtain new analgesic compounds. the final compounds 10a-10e and 15a-15d were prep...

substituted schiff bases (hydrazones) 5a-j have been prepared from the starting material 2-chloro pyridine-3-carboxylic acid 1 by a sequence of reactions like reaction with 2-amino-6-nitro benzothiazole (ullamann condensation), thionyl chloride, hydrazine hydrate and different aromatic aldehydes. on cyclocondensation of 5a-j with thioglycolic acid in dry 1,4-dioxane furnished desired compounds ...

mother's mental health status during pregnancy has important effects on fetal growth and development. however, there are few studies concerning association of maternal depression and biophysical profile (bpp) of the fetus. we performed this research to know if maternal depression has any association with fetal bpp score. for measuring depression, farsi version of patient health questionnaire-9 ...

the recognition of seasonal patterns in infectious disease occurrence dates back at least as far as the hippocratic era, but the mechanisms underlying these fluctuations remain poorly understood. many classes of mechanistic hypotheses have been proposed to explain seasonality of various directly transmitted diseases, including at least the following; human activity, seasonal variability in huma...

malaysia is affected by moderate environmental disasters but seldom affected by severe disaster. cameron highland mud floods 2013, hulu langat landslide 2011, tsunami 2004 and highland tower 1993 are some of environmental disaster in malaysia. some of these disasters carry heavy price tags as property and lives are damaged beyond full compensation and repair and health effects as well. this pap...

synthesis, characterization, spectral and theoretical calculations of sodium tetrafluoroborate (iii) (stfb) has been studied in this research. sodium tetrafluoroborate (iii) was synthesized by a sonochemical method and characterized by ir, uv/vis, 11b-nmr and mass spectrometer techniques. the nano compound was characterized by scanning electron microscopy (sem), x-ray powder diffraction (xrd) a...