AIM Methotrexate (MTX) is an antifolate agent that acts inhibiting purine and pyrimidine synthesis. The objective of the study was to evaluate the viability of Hep-2 human laryngeal cancer cells to the treatment with MTX chemotherapy in vitro. METHODS Cultured Hep-2 cells were treated with 0.25, 25.0 and 75 μM MTX for 24 h, and their viability was evaluated with Bcl-2-FITC antibody in flow cy...

The excess of highest energy solar-neutrino events recently observed by Superkamiokande can be in principle explained by anomalously high hep-neutrino flux Φ ν (hep). Without using SSM calculations, from the solar lumi-nosity constraint we derive that Φ ν (hep)/S 13 cannot exceed the SSM estimate by more than a factor three. If one makes the additional hypothesis that hep neutrino production oc...

We studied the immunophenotype of signet-ring cell carcinoma (SRCC) of the stomach (30 cases), breast (21 cases), and colon (9 cases) with the following expression patterns: (1) breast: consistent, MUC1 (21 [100%]), cytokeratin (CK) 7 (20 [95%]), estrogen receptor (ER; 17 [81%]); infrequent, E-cadherin (6 [29%]), MUC2, MUC5AC, CK20 (1 [5%] each); negative, CDX2 and hepatocyte paraffin 1 (Hep Pa...

Objective To evaluate the radiosensitivity effect of CpG oligodeoxyribonucleotide (ODN) 7909 on human epidermoid cancer strain-2 (Hep-2) cells in vitro and discuss the potential for improved radiotherapy treatment in patients with laryngeal squamous cell carcinoma. Methods Toll-like receptor ( TLR) 9 expression was assessed in Hep-2 cells using Western blots and reverse transcription polymerase...

The matricellular extracellular matrix protein thrombospondin-1 (TSP1) stimulates focal adhesion disassembly through a sequence (known as the hep I peptide) in its heparin-binding domain. This mediates signaling through a receptor co-complex involving calreticulin and low-density lipoprotein (LDL) receptor-related protein (LRP). We postulate that this transition to an intermediate adhesive stat...

We review recent developments and open questions for the description of nonequilibrium quantum fields, continuing hep-ph/0302210 and hep-ph/0410330 [ 1].

Contents 1 Introduction to SCET 4 1. 1 Introduction to SCET These notes provide reading material on the Soft-Collinear Effective Theory (SCET) for Chrisitian's SCET Lectures in TASI 2013. They also served as lecture notes for Iain's 2013 EFT course taught at MIT. The notes assume some familiarity with various basic effective field theory (EFT) concepts, including power counting with operator di...

The influence of cathode materials including carbonaceous electrode on the cathodic mineral scaling behavior in a context wastewater treatment is investigated for first time and particularly thin film microfluidic reactors. kinetics CaCO3 Mg(OH)2 electro-precipitations were evaluated with different (with distinct porosities, electroactive surface area (Selec) hydrogen (H2) evolution overpotenti...

In the domain of high-energy physics (HEP), query languages in general and SQL particular have found limited acceptance. This is surprising since HEP data analysis matches model well: fully structured queried using mostly standard operators. To gain insights on why this case, we perform a comprehensive six diverse, general-purpose processing platforms an benchmark. The result evaluation interes...