To determine the effect of perfluorocarbon (PFC) hemodilution on myocardial vessel capacity to autoregulate, circumflex coronary artery pressure-flow relations were studied in anesthetized dogs under three conditions: maximal vasodilatation before and after PFC; autoregulation before and after PFC with 100% oxygen supplemented with room air ventilation, and autoregulation with PFC hemodilution ...

background: various adverse effects of homologous blood transfusion detected particularly in open heart surgery, in which it is frequently used, lead researchers to study on autologous blood use and to evaluate the patient’s blood better. due to the complications of homologous blood transfusion, development of techniques that utilize less transfusion has become inevitable. we aimed to evaluate ...

background: acute normovolemic hemodilution is an available technique to decrease the side effects of allogenic blood transfusion. the aim of this study was to compare acute normovolemic hemodilution with allogenic blood transfusion in adult patients who were scheduled for femoral fracture surgery. methods: in this randomized controlled trial, 50 patients were randomly allocated into two equal ...

A restrictive approach to blood transfusions is recommended by most current guidelines [1, 2]. Others suggest that in some patients a more liberal transfusion strategy may be beneficial [3]. However, the extensive discussions regarding the appropriate transfusion threshold have not adequately addressed the potential impact of iatrogenic hemodilution on the hemoglobin (Hb) level during dynamic c...