The aims of this study were to determine the occurrence of Anaplasma platys and Ehrlichia canis infection in dogs in Porto Alegre, Southern Brazil; and to investigate their association with hematological abnormalities. Serum samples from 196 dogs were first tested using dot-ELISA for antibodies against Anaplasma spp. and Ehrlichia canis. Peripheral blood samples from 199 dogs were subjected to ...

Decreased expression of the tCR ζ-chain has been reported in several autoimmune and inflammatory diseases. Recent evidence suggests that this deficiency may be due to polymorphisms in the CD247 gene. A total 52 patients with systemic lupus erythematosus (Sle) and 95 healthy controls of Bulgarian ethnicity were genotyped for 837C>g, rs1052230, 844A>t, and rs1052231 using a taqMan genotyping assa...

BACKGROUND Laboratory testing in clinical practice is never a random process. In this study we evaluated testing bias for neutrophil counts in clinical practice by using results from requested and non-requested hematological blood tests. METHODS This study was conducted using data from the Utrecht Patient Oriented Database. This clinical database is unique, as it contains physician requested ...

BACKGROUND International rules must be followed for testing biosecurity in dental materials. A new brand of restorative material appeared in the market and regulations indicated that it should be tested for toxicity. OBJECTIVES The aim of this study was to determine the 90-day sub chronic toxicity of one triethylene glycol dimethacrylate containing composite (MEDENTAL Light-Cure Composite™) o...

OBJECTIVES Panax ginseng has been extensively used as an adaptogen and is among the top 10 selling herbal supplements in the United States over the past decade. However, there have been few reports about the toxicity of P. ginseng in human studies. Given the lack of toxicological studies in human, this study investigated whether P. ginseng administration causes any noticeable toxic effects in h...

In the past, laboratory tests were considered of limited value in Crohn's disease (CD). In the era of biologics, laboratory tests have become essential to evaluate the inflammatory burden of the disease (C-reactive protein, fecal calprotectin) since symptoms-based scores are subjective, to predict the response to pharmacological options and the risk of relapse, to discriminate CD from ulcerativ...

This work aimed to evaluate the chemical composition of essential oils from Catha edulis Forsk collected in Day Forest Republic Djibouti. Additionally, vivo toxicity studies, biochemical profiling, and hematological tests were conducted determine biological activity investigated oils. Finally, vitro performed investigate antibacterial The obtained at yields 0.75%. Chromatographic analysis ident...

BACKGROUND Pregnancy is associated with changes in hematological and biochemistry values, yet there are no African reference intervals for clinical management of pregnant women. We sought to 1) develop laboratory reference intervals during pregnancy and up to 24 weeks postpartum and 2) determine the proportion of women in a previous clinical trial who would be misclassified as having out-of-ran...

Complement fixation (CF) and hematological studies were performed on 517 cows living in normal conditions in different geographical areas of France. The animals belonged to three different categories: (1) multiple or single case herds, in which lymphosarcomas had been detected in the past five years. (2) Leukemia free herds of high risk regions. (3) Leukemia free and apparently unexposed herds....

The diagnostic value of common hematology tests in differentiating between thalassemia trait and iron-deficiency anemia (IDA) was assessed. Serum iron concentration was included in a second stage of the diagnostic model and its predictive contribution was determined. After applying discriminant analysis to the data, minimization of Wilks's lambda (lambda) criterion was used to select the best p...