Nowadays, energy consumption increases so it is necessary to enhance the efficiency and performance of heat transition. The effects perforated twisted tape on transfer coefficient, effectiveness, Nusselt number, pressure drop are studied numerically. Modeling exchanger with applied where finite volume method utilized perform setup complete solution. numerical results validated previous experime...

Abstract Various combinations of objective functions and design variables have been considered in several optimization studies ground heat exchangers (GHEs). In this study, the optimum values coil pitch diameter a helical-shaped GHE were determined to maximize its convection transfer rate. Central composite was used determine dimensions be modeling. Nine models generated Fusion360 which then ex...

The MaxFlux reaction path algorithm was used to isolate optimal transition pathways for the coil-to-helix transition in polyalanine. Eighteen transition pathways, each connecting one random coil configuration with an ideal alpha-helical configuration, were computed and analyzed. The transition pathway energetics and mechanism were analyzed in terms of the progression of the peptide nonbonded co...

Random coil chemical shifts are commonly used to detect protein secondary structural elements in chemical shift index (CSI) calculations. Though this technique is widely used and seems reliable for folded proteins, the choice of reference random coil chemical shift values can significantly alter the outcome of secondary structure estimation. In order to evaluate these effects, we present a comp...

Abstract Helical coil accelerators are a recent development in laser-driven ion production, acting on the intrinsically wide divergence and broadband energy spectrum of laser-accelerated protons to deliver ultra-low quasi-monoenergetic beams. The modularity helical also provides attractive prospective multi-staging. Here we show, proof-of-principle basis, two-stage configuration which allows op...

A novel strategy for in vivo immobilization of enzymes on the surfaces of inclusion bodies has been established. It relies on expression in Escherichia coli of the polyhydroxybutyrate synthase PhaC from Cupriavidus necator, which carries at its amino terminus an engineered negatively charged alpha-helical coil (Ecoil) and forms inclusion bodies upon high-level expression. Coexpression in the sa...

Biological molecules can form hydrogen bonds between nearby residues, leading to helical secondary structures. The associated reduction of configurational entropy leads to a temperature dependence of this effect: the helix-coil transition. Since the formation of helices implies a dramatic shortening of the polymer dimensions, an externally imposed end-to-end distance R affects the equilibrium h...