BACKGROUND The aim of the present study was to estimate minimally important differences (MIDs) in EQ-5D and SF-6D indices and to explore the responsiveness of EQ-5D and SF-6D indices in stroke. METHODS We used observational longitudinal survey data of EQ-5D and SF-36 that were administered to stroke patients at baseline and at 10 months. A range of MIDs for both indexes was estimated using an...

BACKGROUND The prevalence of osteoarthritis and knee osteoarthritis in the Spanish population is estimated at 17% and 10.2%, respectively. The clinical guidelines concur that the first line treatment for knee osteoarthritis should be non-pharmacological and include weight loss, physical activity and self-management of pain. Health Coaching has been defined as an intervention that facilitates th...

BACKGROUND To estimate the long-term change in health related quality of life (HRQoL) following low-trauma fractures among individuals receiving home care (HC) services or living in long-term care (LTC) facilities using linked healthcare administrative data from Ontario, Canada. METHODS HRQoL was estimated using the Health Utility Index (HUI-2) with the InterRai Minimum Data Set (MDS), a mand...

To assess the face validity of a decision-analytic model evaluating cost-utility ataluren for treatment nonsense mutation Duchenne muscular dystrophy (nmDMD). This was Delphi panel comprising physicians with first-hand experience nmDMD. Consensus investigated key parameters, including expected benefit early treatment, mortality, informal caregiving, and patient health status quality life (asses...

OBJECTIVE To conduct a meta-analysis of the cost-utility of the cochlear implant in adults. DATA SOURCES MEDLINE literature search, review of article bibliographies, and consultation with experts. STUDY SELECTION Studies that reported (1) data on adults (age > or = 18 years) with bilateral, postlingual, profound deafness; (2) a health-utility gain from cochlear implantation on a scale from ...

BACKGROUND Health state utility values (HSUVs) are essential parameters in model-based economic evaluations. This study systematically identifies HSUVs in head and neck cancer and provides guidance for selecting them from a growing body of health-related quality of life studies. METHODS We systematically reviewed the published literature by searching PubMed, EMBASE and The Cochrane Library us...