Chronic hepatitis C virus (HCV) infection is estimated to affect 57 million people globally.1 Despite the availability of safe and effective pan-genotypic direct acting antivirals,2-5 many countries have yet achieve WHO goal HCV elimination by 2030.1

Background and aim: An epidemiological association of lichen planus (LP) with hepatitis C virus (HCV) infection has been found only in certain parts of the world and in some countries no association has been noted. The present study was done to evaluate the association of LP with HCV in patients admitted to Sina hospital, Hamedan, Iran from 2002 to 2004.Materials and Methods: The presence of an...

HCV-induced hepatitis is one of the most debilitating diseases. The limited number of anti-HCV drugs and drug-resistance necessitate developing of new scaffolds with different mode of actions. HCV non-structural protein 5B (NS5B) is an attractive target for development of novel inhibitors of HCV replication. In this paper, new N'-arylidene-6-(benzyloxy)-4-oxo-1,4-dihydroquinoline-3-carbohydrazi...

Background and Aims: Co-infection of hepatitis E virus (HEV) in chronic hepatitis C virus (HCV) infected patients can develop and increase liver disease and hepatic complications in the world. The purpose of this study was to assess the prevalence of HEV infection in patients suffering from chronic HCV infection. Materials and Methods: Cross-sectional study testing anti-HEV antibodies in serum...

To estimate the prevalence of women who tested positive for HCV in pregnancy during periods risk-based screening (RBS) and universal screening. number a period reported risk factors (RF). This is retrospective, single-center cohort study 9569 from 2/2016-12/2018 RBS & at one ObGyn Center. Study subjects were identified by initial prenatal visits performed physician/NP through EMR. Chart reviews...

Data about co-infection of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2), HIV, and hepatitis C virus (HCV) are still scarce. We describe a patient hospitalized for sore throat, fatigue, myalgia with personal history HIV occult HBV infection. His antiretroviral therapy included bictegravir/emtricitabine/tenofovir alafenamide. The nasopharyngeal swab was positive SARS-CoV-2...

Hepatitis C virus (HCV) infection affects kidneys with different histopathological patterns on kidney biopsy, which commonly include membranoproliferative glomerulonephritis (MPGN) pattern mixed cryoglobulinemia (CG), thrombotic microangiopathy, membranous nephropathy and small to medium vessel vasculitis. Type 1 MPGN associated type II CG is the most common glomerulopathy hepatitis infection. ...

Background: HCV chronic infection is a leading cause of end-stage liver disease and transplantation. The aim our study was to assess the benefits novel anti-HCV therapeutic approaches in obtaining viral clearance, reducing inflammation, regression fibrosis, improvement liver-related morbidity mortality.