Cell division is a process by which a mother cell divides into genetically identical sister cells, although sister cells often display considerable diversity. In this report, over 350 sister embryonic stem cells (ESCs) were isolated through a microdissection method, and then expression levels of 48 key genes were examined for each sister cell. Our system revealed considerable diversities betwee...

the clinical and phenotypic features of two siblings (a 12 years old girl and her 7 year old brother) with cockayne syndrome are described. the main problems were mild to moderate mental retardation, dwarfism, clumsy gait, photosensitive skin lesions and progeroid (senile like) appearance. brain ct - scans revealed symmetrical, well defined areas of calcification mainly located at lenticular nu...

Man wolle dabei von der Arbeit, die Herr Dr. Hellinger zu erledigen hatte, nicht gering denken. Denn es ist auch so noch ein weiter Weg von der durch allerlei zufällige Umstände bedingten mündlichen Darlegung des Dozenten zu der schriftlichen, hinterher noch wesentlich abgeglichenen, lesbaren Darstellung. [One should not underestimate the work that Dr. Hellinger had to accomplish. It is a long ...

To my parents and my sister i ACKNOWLEDGEMENTS I thank my advisor, Dr. Nikil Jayant for teaching me how to be successful in the technological world, and for having complete faith in me right from the start to the finish of my PhD, and beyond. I would like to take the opportunity to thank my committee members, Dr. Constantine Dovrolis for being an integral part of my doctoral degree. I wish to t...