This paper proposes that atherosclerosis is initiated by a signaling event that deposits calcium hydroxyapatite (Ca-HAP). This event is preceded by a loss of mechanical structure in the arterial wall. After Ca-HAP has been deposited, it is unlikely that it will be reabsorbed because the solubility product constant (Ksp) is very small, and the large stores of Ca +2 and PO4 −3 in the bones oppose...

Heteroaryldihydropyrimidines (HAPs) are a new class of antivirals inhibiting production of hepatitis B virus (HBV) virions in tissue culture. Here, we examine the effect of a representative HAP molecule, methyl 4-(2-chloro-4-fluorophenyl)-6-methyl-2-(pyridin-2-yl)-1,4-dihydropyrimidine-5-carboxylate (HAP-1), on the in vitro assembly of HBV capsid protein (Cp). HAP-1 enhances the rate and extent...

Hydroxyapatite (HAp), a major inorganic component of hard tissues, has been widely used as a novel scaffold for bone or tooth tissue regeneration. However, the effects of HAp on dental cells at the molecular level are poorly understood. In the present study, we evaluated the effects of HAp on differentiationand mineralization-related gene expression in the dental epithelial cell line (HAT-7). H...

Flue gas desulfurization gypsum (FGD) is a waste material arouse from coal power plants. Hydroxyapatite (HAP) is a biomaterial with porous structure. In this study, FGD gypsum which retrieved from coal power plant in Turkey was characterized and HAP particles which can be used as an adsorbent in wastewater treatment application were synthesized from the FGD gypsum. The raw materials are charact...

Liquid crystals are mostly formed by self-assembly of organic molecules. In contrast, inorganic materials available as liquid crystals are limited. Here we report the development of liquid-crystalline (LC) hydroxyapatite (HAp), which is an environmentally friendly and biocompatible biomineral. Its alignment behavior, magneto-optical properties, and atomic-scale structures are described. We succ...

Conditions are described for the reproducible assay of substances affecting the in vitro rate of aggregation of isolated chick embryo hepatocytes. Two low molecular weight (less than 1000) fractions--one that promotes hepatocyte aggregation (HAP) and the other that inhibits this stimulation (HAI)--have been isolated and partially purified from adult chicken liver. One major active component of ...

IL-17A is a pro-inflammatory cytokine that has been implicated in autoimmune and inflammatory diseases. Monoclonal antibodies inhibiting IL-17A signaling have demonstrated remarkable efficacy, but an oral therapy is still lacking. A high affinity IL-17A peptide antagonist (HAP) of 15 residues was identified through phage-display screening followed by saturation mutagenesis optimization and amin...

Recently, a hash-chain based authentication protocol has been proposed, named HAP, in vehicular communications to improve the scalability. By means of removing certificate cost, HAP earns a great performance in terms of computational overhead and message loss ratio. Unfortunately, we discover a fatal security flaw that malicious vehicles can masquerade as an innocent one to disseminate forged m...

Hydroxyapatite (HAP) is a main mineral constituent of bone and tooth and has an outstanding biocompatibility. HAP is a possible sorbent for heavy metals in wastewater due to its high adsorption capacity and low water solubility. We developed a removal system of 90Sr from aqueous solution by HAP column procedure. More than 90 % of 90Sr was adsorbed and removed from the 90Sr containing solution. ...

The aim of this paper is to show the possible coexistence of an HAP and a terrestrial component of 3G networks at a single carrier frequency. The main goal is to compare the basic parameters of terrestrial and HAP component 3G networks modeled in suburban (macrocell) and urban (macro/microcell) areas and to demonstrate the way they impact on each other. This study should present what we assume ...