Eccrine angiomatous hamartoma is a rare hamartomatous lesion characterized by proliferation of eccrine glands and small blood vessels, and occasionally other elements. It generally arises congenitally or later in childhood, as solitary or multiple lesions on the distal extremities. Adult-onset multiple lesions are very rare. Herein we describe a 33-year-old male with symptomatic multiple eccrin...

Peutz-Jeghers syndrome (PJS, MIM 175,2000) is a disease of autosomal dominant inheritance that is characterised by hamartomatous gastrointestinal polyps and mucocutaneous pigmentation. In addition to problems such as intussusception, PJS predisposes to cancers of several sites. The unusual combination of clinical features makes the identification of the defect underlying PJS particularly intere...

MR imaging of four children with neurofibromatosis demonstrated areas of increased T2 signal involving widespread multifocal regions of basal ganglia and brainstem. Such abnormalities have not been previously reported. No corresponding CT abnormalities were present. These regions may represent hamartomatous or low-grade gliomatous change, and appear to be characteristic of neurofibromatosis in ...

▼ BENIGN “VIRUS-INDUCED” TUMORS (ORAL SQUAMOUS PAPILLOMAS AND WARTS) ▼ SYNDROMES WITH BENIGN ORAL NEOPLASTIC OR HAMARTOMATOUS COMPONENTS Von Recklinghausen’s Neurofibromatosis Gardner’s Syndrome Peutz-Jeghers Syndrome Nevoid Basal Cell Carcinoma Syndrome Multiple Endocrine Neoplasia Type III (Multiple Mucosal Neuroma Syndrome) Tuberous Sclerosis Acanthosis Nigricans Albright’s Syndrome Paget’s ...

Syringocystadenoma papilliferum (SCAP) is a benign hamartomatous tumor arising from pluripotent cells with either apocrine or eccrine differentiation. We report a rare case of de novo linear SCAP in a 12-year-old female child with lesions over the chest along with the dermoscopic findings.

A macrocephalic girl presented with generalised epilepsy due to focal cortical dysplasia. She later developed multiple hamartomatous lesions and was diagnosed to have Cowden syndrome. The diagnosis was confirmed by identification of a novel frameshift mutation in the PTEN gene of the patient.