Sometimes, when carrying out a preliminary computation in order to be sure that well understood llimits of a problem are handled correctly, results which are interesting in their own right emerge. I will now discuss one such result which I have obtained as part of such a preliminary study of the Hubbard model. The Hubbard model at halflling is equivalent to a Heisenberg anti-ferromagnet (HAF) a...

Nanogels (NG) hold great promise as a drug delivery platform. In this work, we examine the potential of lysozyme-dextran nanogels (LDNG) as drug carriers in vitro using two cell lines: a model target tissue, human umbilical cord vein endothelial cells (HUVEC) and a model of the mononuclear phagocyte system (phorbol 12-myristate 13-acetate (PMA)-stimulated THP-1 cells). The LDNG (∼100 nm) were p...

Stress corrosion cracking (SCC) of metals is an issue of major concern in engineering since this phenomenon causes many catastrophic failures of structural components in aggressive environments. SCC is even more harmful under cathodic conditions promoting the phenomenon known as hydrogen assisted cracking (HAC), hydrogen assisted fracture (HAF) or hydrogen embrittlement (HE). A common way to as...

Cells respond to defects in mitochondrial function by activating signaling pathways that restore homeostasis. The mitochondrial peptide exporter HAF-1 and the bZip transcription factor ATFS-1 represent one stress response pathway that regulates the transcription of mitochondrial chaperone genes during mitochondrial dysfunction. Here, we report that GCN-2, an eIF2α kinase that modulates cytosoli...

Background. Several approaches have been proposed to pharmacologically ameliorate hepatic ischemia/reperfusion injury (IRI). This study was designed to evaluate the effects of a preconditioning oral nutritional supplement (pONS) containing glutamine, antioxidants, and green tea extract on hepatic warm IRI in pigs. Methods. pONS (70 g per serving, Fresenius Kabi, Germany) was dissolved in 250 mL...

The emergence and development of induced pluripotent stem cells (iPSCs) provides an approach to understand the regulatory mechanisms cell pluripotency demonstrates great potential iPSCs in disease modeling. Acute myelitis defines a group inflammatory diseases that cause acute nerve damage spinal cord; however, its pathophysiology remains be elusive. In this study, we derived skin fibroblasts fr...

The Contractor Renormalization group formalism (CORE) is a real-space renormalization group method which is the Hamiltonian analogue of the Wilson exact renormalization group equations. In an earlier paper[3] I showed that the Contractor Renormalization group (CORE) method could be used to map a theory of free quarks, and quarks interacting with gluons, into a generalized frustrated Heisenberg ...

The relationship between the changes in portal venous and hepatic arterial blood flows, in the liver is a much disputed question, it has tremendous significance in the practice of transplantation, and an explanation has been available since 1981, when Lautt published the so-called "adenosine washout theory". According to our earlier observations the decrease of portal pressure or flow consisten...

Background: The ethano-pharmacological survey on two Indian medicinal plants Alternanthera ficoidea and Ludwigia octovalvis revels that both are biologically potential effective in the management of various diseases. Despite as whole used traditionally by local people subcontinent but toxicity studies plant extract has not explored scientifically. Objective: study was designed to explore associ...