نتایج جستجو برای: h9

تعداد نتایج: 732  

Journal: :Frontiers in Cell and Developmental Biology 2021

The generation of transplantable hematopoietic stem cells (HSCs) from human pluripotent (hPSCs) remains challenging. Current differentiation protocols hPSCs generate mostly progenitors the primitive HSC-independent program, and it unclear what is best combination cytokines growth factors (HGFs) for obtaining functional in vitro . Here, we have used AND1 H9 hESC lines H9:dual-reporter RUNX1C -GF...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه شیراز - دانشکده دامپزشکی 1388

به منظور ایمنی وسیع الطیف بر علیه سویه ها و واریته های مختلف ویروس آنفلونزای تیپ a ، اخیرا پروتئین m2 از ویروس آنفلونزا محققان قرار گرفته است. لذا در این تحقیق orf ژن m2 از سوش واکسینال رازی (a/chicken/iran/101/1998 (h9n2 بکمک دو پرایمر اختصاصی که دارای سایتهای برشی برای آنزیمهایndei و ecori بودند و با استفاده ازتکنیک مولکولی rt-pcr دو مرحله ای تکثیر گردیده و در وکتور بیانی paed4 قرار داده و در...

Journal: :Bioorganic & medicinal chemistry 2013
Tsukasa Mizuhara Shinya Oishi Hiroaki Ohno Kazuya Shimura Masao Matsuoka Nobutaka Fujii

To investigate the mechanism of action of the potent antiviral compound PD 404182, three novel photoaffinity probes equipped with a biotin or alkyne indicator were designed and synthesized based on previous structure-activity relationship studies. These probes retained the potent anti-HIV activity of the original pyrimidobenzothiazine derivatives. In photoaffinity labeling studies using HIV-1-i...

Journal: :Journal of the Japanese Association for Infectious Diseases 1991

Journal: :Biochemical Society transactions 1989
A Aitken

In conclusion, our results show that inhibitors of acylation may be developed on the basis of analogues of myristic acid. Such inhibitors inhibit not only the N-myristoyl transferase activity, but also acylation of proteins in intact cells. They are also able to inhibit virus acylation. Preliminary results show that they inhibit HIV release from infected H9 cells in culture and therefore may be...

2015
Camille Lebarbenchon Audrey Jaeger Chris Feare Matthieu Bastien Muriel Dietrich Christine Larose Erwan Lagadec Gérard Rocamora Nirmal Shah Hervé Pascalis Thierry Boulinier Matthieu Le Corre David E. Stallknecht Koussay Dellagi Daniel R. Perez

Ducks and seabirds are natural hosts for influenza A viruses (IAV). On oceanic islands, the ecology of IAV could be affected by the relative diversity, abundance and density of seabirds and ducks. Seabirds are the most abundant and widespread avifauna in the Western Indian Ocean and, in this region, oceanic islands represent major breeding sites for a large diversity of potential IAV host speci...

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