INTRODUCTION Vitamin E is beneficial in restoring bone histomorphometric parameters in nicotine-treated rats. This study determined the effectiveness of 3 forms of vitamin E in restoring bone metabolism in nicotine-treated rats. MATERIAL AND METHODS Thirty-five male Sprague-Dawley rats were divided into 5 groups: (1) control (C), (2) nicotine cessation (NC), (3) α-tocopherol (ATF), (4) tocotr...

BACKGROUND Methods to identify preventable adverse events typically have low yield and efficiency. We refined the methods of Institute of Healthcare Improvement's Global Trigger Tool (GTT) application and leveraged electronic health record (EHR) data to improve detection of preventable adverse events, including diagnostic errors. METHODS We queried the EHR data repository of a large health sy...

AIMS Alcohol has deleterious influences on glucose metabolism which may contribute to the development of type 2 diabetes mellitus (T2DM). Insulin-like growth factor I (IGF-I) and growth hormone (GH), which interact with insulin to modulate metabolic control, have been shown to be related to impaired glucose tolerance. This study was conducted to assess the possibility that altered circulating I...

Prevention of arterial thrombotic disorders is a very important socioeconomic challenge. The most convenient way of prevention could be by dietary means. In testing diets for antithrombotic effect, selection of pathologically relevant models of arterial thrombosis is of crucial importance. We demonstrated that the shear-induced platelet-rich thrombosis/thrombolysis in vitro/ex vivo test, Global...

BACKGROUND The second generation antipsychotic (SGA) drugs are widely used in psychiatry due to their clinical efficacy and low incidence of neurological side-effects. However, many drugs in this class cause deleterious metabolic side-effects. Animal models accurately predict metabolic side-effects for SGAs with known clinical metabolic liability. We therefore used preclinical models to evaluat...

Introduction While the vast majority of clinical MRI sequences utilize Cartesian sampling strategies, in a growing number of applications nonCartesian schemes are being employed for a variety of technical reasons. For example, our own motivation is diffusion tensor imaging (DTI) wherein we use spiral trajectories [1], in part because they facilitate efficient self-navigation schemes for artifac...

Amaç: Son yıllarda dünyada ve ülkemizde “Geleneksel Tamamlayıcı Tıp” (GTT) uygulamalarında ürünlerinin kullanımında artış izlenmektedir. Hekimler GTT uygulamalarının gerekliliği, yararları veya olası komplikasyonları konusunda tam bir görüş birliğine sahip değildir. Bu çalışmada çocuk hekimlerinin uygulamaları konusundaki bilgi görüşlerini değerlendirmek amaçlanmıştır.
 
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Previous studies have shown that the clove essential oil concentration of 200 mg/kg did not present toxicity and histopathological changes in liver. Based on evidence presented this study, we decided to evaluate vivo ability a previously developed fermented dairy beverage, tested only vitro, which standard chemical preservative, potassium sorbate, was replaced by (2 μl/ml), be functional food. ...

To assess whether women with gestational diabetes (GDM) should be screened the glucose tolerance test (GTT) instead of challenge (GCT) as primary in next pregnancy. This is an IRB-exempt retrospective cohort study. We included GDM who had a subsequent delivery at our institution from 2004-2020. Patients BMI < 18.5 kg/m2, multifetal gestation, pregestational mellitus and chronic hypertension wer...

Abstract Gradually typed languages are designed to support both dynamically and statically programming styles while preserving the benefits of each. Sound gradually check types at runtime boundary between modules. However, there is much disagreement in gradual typing literature over how enforce complex such as tuples, lists, functions objects. In this paper, we propose a new perspective on desi...