The present study was designed to investigate the expression of GSTs under the influence of paracetamol and Hybanthus enneaspermus. Study with different substrates of glutathione-s-transferases were done to know the expression of GSTs. Along with this purification and isolation of GSTs were performed to know the expression of subunits of liver GSTs.Three subunits were found. Newly π GSTs were e...

کچ ي هد دنب هعطق شور كي هلاقم نيا رد ي واصت ي گنر ر ي هقبط زا هدافتسا اب ريگداي ياتاموتا رب ينتبم يزاف هدننک يدنب م داهنشيپ يلولس ي ددرگ . نيا رد هقبط نيناوق و تيوضع عباوت يلولس ريگداي ياهاتاموتا زا يا هعومجم كمك هب هدننک يدنب يم ديلوت کيتاموتا روط هب يزاف دنوش . ا يلولس ريگداي ياتاموتا ز نِگمه ان مِاگمهان هب زاب نيرتهب نتفاي يارب يرازبا ناونع تسا هدش هدافتسا يزاف تيوضع عباوت راتخاس . رد اتاموت...

Glutathione S-transferases (GSTs) are abundant proteins encoded by a highly divergent, ancient gene family. Soluble GSTs form dimers, each subunit of which contains active sites that bind glutathione and hydrophobic ligands. Plant GSTs attach glutathione to electrophilic xenobiotics, which tags them for vacuolar sequestration. The role of GSTs in metabolism is unclear, although their complex re...

In the present paper, we report a novel class of GSTs (glutathione transferases), called the Chi class, originating from cyanobacteria and with properties not observed previously in prokaryotic enzymes. GSTs constitute a widespread multifunctional group of proteins, of which mammalian enzymes are the best characterized. Although GSTs have their origin in prokaryotes, few bacterial representativ...

Glutathione transferases (GSTs) are ubiquitous scavengers of toxic compounds that fall, structurally and functionally, within the thioredoxin fold suprafamily. The fundamental catalytic capability of GSTs is catalysis of the nucleophilic addition or substitution of glutathione at electrophilic centers in a wide range of small electrophilic compounds. While specific GSTs have been studied in det...

Glutathione S-transferases (GSTs) are a superfamily of multifunctional enzymes, widely distributed in living organisms. Recently, more and more insect genome sequences are available. Genomic characterizations and comparative analyses of insect GSTs have been performed. In addition, application of high-throughput technologies, such as microarray and next-generation sequencing technology, have ac...