Recently we have shown the antiproliferative activity of Gleditsia sinensis fruit extract (GSE) on various solid tumour and leukaemia cell lines as well as primary cultured bone marrow cells isolated from patients with acute and chronic myelogenous leukaemia. We further studied whether the growth inhibitory effect of GSE involves basic fibroblast growth factor (bFGF) in cancer cell lines includ...

OBJECTIVE General self-efficacy has been found to be an influential variable related to the adaptation to stress and chronic illness, with the General Self-Efficacy (GSE) Scale by Jerusalem and Schwarzer being a reliable and valid instrument to assess this disposition. The aim of this study was to construct and test a short form of this scale to allow for a more economical assessment of the con...

OBJECTIVE(S) Cerebral hypoperfusion/ischemia (CHI) is a neurological disease where impaired hippocampus electrical activity and cognition caused by a serial pathophysiological events. This study aimed to evaluate the effects of chronic oral administration of grape seed extract (GSE) on passive avoidance memory and long-term potentiation (LTP) after permanent bilateral common carotid arteries oc...

OBJECTIVES Grapefruit-seed extract (GSE) Citricidal has, in recent reports, been reported to be successful in combating a variety of common infectious agents. In our study, drops of concentrated grapefruit-seed extract were tested for antibacterial properties against a number of gram-positive and gram-negative organisms. DESIGN Sixty-seven (67) distinct biotypes were tested for their suscepti...

The aim of the study is to identify useful Knowledge Management (KM) practices/tools in order to overcome Requirements Understanding (RU) challenges in Global Software Engineering (GSE). As Requirements Engineering (RE) is considered one of the most crucial, human intensive and challenging phase of software engineering. A paradigm shift from traditional co-located to offshore development has in...

Although flavonoids manifest a diverse range of biological activities, including antitumor and antiviral effects, the molecular mechanisms underlying these activities await elucidation. We hypothesize that the flavonoid constituents of a proprietary grape seed extract (GSE) that contains procyandins exert significant antiviral and antitumor effects, by inducing production of the Th1-derived cyt...

Cytoprotective effects of short-term treatment with grape seed extract (GSE) upon human gingival fibroblasts (hGFs) were evaluated in relation to its antioxidant properties and compared with those of a water-soluble analog of vitamin E: trolox (Tx). GSE and Tx showed comparable antioxidant potential in vitro against di(phenyl)-(2,4,6-trinitrophenyl)iminoazanium (DPPH; a stable radical), hydroxy...

BACKGROUND/AIMS Drinking red wine is associated with a decreased mortality from coronary heart diseases. This study examined whether polyphenols contained in a grape skin extract (GSE) triggered the endothelial formation of nitric oxide (NO) and investigated the underlying mechanism. METHODS Vascular reactivity was assessed in organ chambers using porcine coronary artery rings in the presence...

Abstract We report a correlation between the presence of Gaia-Sausage-Enceladus (GSE) analogue and dark matter halo spin in artemis simulations Milky Way-like galaxies. The haloes which contain large population accreted stars on highly radial orbits (like GSE) have lower average than their counterparts with more isotropic stellar velocity distributions. median modified parameters λ′ differ by f...

This draft has three objectives: (1) to discuss the impact of multihoming on the scalability of the global routing system; (2) to provide an overview of GSE, one of the early proposals by Mike O'Dell to address the multihoming scalability problem; and (3) to identify open issues raised by the GSE proposal, which may serve as a first step towards resolving them.